GPR132

Gene Symbol GPR132
Entrez Gene 29933
Alt Symbol G2A
Species Human
Gene Type protein-coding
Description G protein-coupled receptor 132
Other Description G2 accumulation protein|probable G-protein coupled receptor 132
Swissprots Q9UNW8 B4E144 A8K7X7 Q9BSU2
Accessions CAH25932 CAH25933 EAW81898 Q9UNW8 AA714520 AB465599 BAG84609 AB465600 BAG84610 AF083955 AAD47380 AK292142 BAF84831 AK303654 BAG64656 AX775841 CAE11620 AX775935 CAE11667 AX775939 CAE11669 BC004555 BC084546 AAH84546 BT007257 AAP35921 DB137292 EU432121 ABY87920 EU543705 ACC61682 W15172 NM_001278694 NP_001265623 NM_001278695 NP_001265624 NM_001278696 NP_001265625 NM_013345 NP_037477
Function May be a receptor for oxidized free fatty acids derived from linoleic and arachidonic acids such as 9- hydroxyoctadecadienoic acid (9-HODE). Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May function as a sensor that monitors the oxidative states and mediates appropriate cellular responses such as secretion of paracrine signals and attenuation of proliferation. May mediate ths accumulation of intracellular inositol phosphates at acidic pH through proton- sensing activity. {ECO:0000269|PubMed:12586833, ECO:0000269|PubMed:19855098, ECO:0000269|PubMed:9770487}.
Subcellular Location Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Internalized and accumulated in endosomal compartments. LPC triggers the relocalization from the endosomal compartment to the cell surface (By similarity). {ECO:0000250}.
Tissue Specificity Highly expressed in macrophages and hematopoietic tissues rich in lymphocytes, like spleen and thymus. Weakly expressed in heart and lung. In atherosclerotic plaques, expression is observed around the lipid core and at the shoulder region. {ECO:0000269|PubMed:12482833}.

G2A (N-20) - sc-19488 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

G2A (A-20) - sc-23810 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
G2A (A-20): sc-23810. Western blot analysis of G2A expression in CTLL-2 (A) and TK-1 (B) whole cell lysates.

G2A (G-5) - sc-137112 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
G2A (G-5): sc-137112. Western blot analysis of G2A expression in rat skeletal muscle tissue extract.

G2A (H-70) - sc-50309 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
G2A (H-70): sc-50309. Immunoperoxidase staining of formalin fixed, paraffin-embedded human epididymis tissue showing membrane and cytoplasmic staining of glandular cells.

Anti-GPCR G2A antibody - ab136237 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-GPCR G2A antibody (ab136237) at 1/500 dilution + HT29 cell lysates at 30 µg

Anti-GPCR G2A antibody - ab116586 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry Image of Human Spleen (formalin-fixed, paraffin-embedded) stained with GPCRG2A antibody (ab116586)at 11 &microg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-GPCR G2A antibody - C-terminal - ab188942 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human spleen, red pulp tissue labeling GPCR G2A with ab188942 at 10 µg/ml.

Anti-GPCR G2A antibody - Extracellular domain - ab150509 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human spleen tissue labeling GPCR G2A with ab150509 at 28 µg/ml.

Anti-GPR132 / G2A Antibody (Internal) IHC-plus™ - LS-A1605 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GPR132 / G2A antibody LS-A1605 IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-GPR132 / G2A Antibody (C-Terminus) IHC-plus™ - LS-A1604 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GPR132 / G2A antibody LS-A1604 IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-GPR132 / G2A Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A1600 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GPR132 / G2A antibody IHC of human Lymph Node, Non-Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-GPR132 / G2A Antibody (Extracellular Domain) IHC-plus™ - LS-A3702 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GPR132 / G2A antibody LS-A3702 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-GPR132 / G2A Antibody (aa301-350) - LS-C292007 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GPR132 / G2A Antibody (Lys327) - LS-C177094 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of G2A (K327) pAb in extracts from COS-7 cells.

Anti-GPR132 / G2A Antibody (aa293-342) - LS-C199008 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from COS7 cells, using GPR132 Antibody. The lane on the right was incubated with synthetic peptide.

Anti-GPR132 / G2A Antibody (aa311-360) - LS-C120683 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from Jurkat cells, using GPR132 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-GPR132 / G2A Antibody (C-Terminus) IHC-plus™ - LS-A3701 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-GPR132 / G2A antibody LS-A3701 IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

G2A/GPR132 Antibody - NBP1-89808 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: G2A/GPR132 Antibody [NBP1-89808] - Staining of human lymph node shows cytoplasmic positivity in germinal center cells and non-germinal center cells.

G2A/GPR132 Antibody - NBP1-89807 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: G2A/GPR132 Antibody [NBP1-89807] - Staining of human lymph node shows strong cytoplasmic positivity in non-germinal center cells.

G2A/GPR132 Antibody - NLS3702 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: G2A/GPR132 Antibody [NLS3702] - Analysis of anti-GPR132 / G2A antibody with human spleena at 3 ug/ml.

G2A/GPR132 Antibody - NBP1-02347 from Novus Biologicals

Prices $329.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: G2A/GPR132 Antibody [NBP1-02347] - Staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 11 ug/ml.

G2A/GPR132 Antibody - NLS1600 from Novus Biologicals

Prices $329.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: G2A/GPR132 Antibody [NLS1600] - Analysis of anti-GPR132 / G2A antibody with human lymph node, Hodgkins lymphoma.

GPCR G2A Polyclonal Antibody - bs-13508R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GPCR G2A Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13508R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GPCR G2A Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13508R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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