GPR132

Gene Symbol	GPR132
Entrez Gene	29933
Alt Symbol	G2A
Species	Human
Gene Type	protein-coding
Description	G protein-coupled receptor 132
Other Description	G2 accumulation protein|probable G-protein coupled receptor 132
Swissprots	Q9UNW8 B4E144 A8K7X7 Q9BSU2
Accessions	CAH25932 CAH25933 EAW81898 Q9UNW8 AA714520 AB465599 BAG84609 AB465600 BAG84610 AF083955 AAD47380 AK292142 BAF84831 AK303654 BAG64656 AX775841 CAE11620 AX775935 CAE11667 AX775939 CAE11669 BC004555 BC084546 AAH84546 BT007257 AAP35921 DB137292 EU432121 ABY87920 EU543705 ACC61682 W15172 NM_001278694 NP_001265623 NM_001278695 NP_001265624 NM_001278696 NP_001265625 NM_013345 NP_037477
Function	May be a receptor for oxidized free fatty acids derived from linoleic and arachidonic acids such as 9- hydroxyoctadecadienoic acid (9-HODE). Activates a G alpha protein, most likely G alpha(q). May be involved in apoptosis. Functions at the G2/M checkpoint to delay mitosis. May function as a sensor that monitors the oxidative states and mediates appropriate cellular responses such as secretion of paracrine signals and attenuation of proliferation. May mediate ths accumulation of intracellular inositol phosphates at acidic pH through proton- sensing activity. {ECO:0000269|PubMed:12586833, ECO:0000269|PubMed:19855098, ECO:0000269|PubMed:9770487}.
Subcellular Location	Cell membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Note=Internalized and accumulated in endosomal compartments. LPC triggers the relocalization from the endosomal compartment to the cell surface (By similarity). {ECO:0000250}.
Tissue Specificity	Highly expressed in macrophages and hematopoietic tissues rich in lymphocytes, like spleen and thymus. Weakly expressed in heart and lung. In atherosclerotic plaques, expression is observed around the lipid core and at the shoulder region. {ECO:0000269|PubMed:12482833}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GPR132 / G2A Antibody Blocking Peptide - LS-E28797 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPR132 / G2A Antibody Blocking Peptide - LS-E28798 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPR132 / G2A Antibody Blocking Peptide - LS-E28348 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPR132 / G2A Antibody Blocking Peptide - LS-E28349 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPR132 / G2A Antibody Blocking Peptide - LS-E28350 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GPR132 Blocking Peptide - abx063840 from Abbexa Category Peptide Species Human

GPR132 / G2A - H00029933-G01 from Acris Antibodies Category Protein Prices $440.00 Sizes 2 µg Species Human

GPR132 / G2A - H00029933-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

GPR132 / G2A - H00029933-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

GPR132 fusion protein - ag10325 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

GPR132 fusion protein - ag10191 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

GPR132 Blocking Peptide - CBP2646 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

G2A (K327) Peptide - BS2607P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human G2A/GPR132 Protein - H00029933-G01 from Novus Biologicals Category Protein Prices $415.00 Sizes 2 µg Source Wheat Germ Species Human

G2A/GPR132 Recombinant Protein Antigen - NBP1-89808PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

G2A/GPR132 Recombinant Protein Antigen - NBP1-89807PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

GPR132 Peptide, Human - M34GP06524H from Creative Peptides Category Peptide Source Synthetic. Species Human

Probable G-protein coupled receptor 132 (GPR132), Recombinant Protein - MBS7016077 from MyBioSource Category Protein Prices $1,185.00, $2,175.00, $3,380.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

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