Gene Symbol | DEFA3 |
---|---|
Entrez Gene | 1668 |
Alt Symbol | DEF3, HNP-3, HNP3, HP-3, HP3 |
Species | Human |
Gene Type | protein-coding |
Description | defensin, alpha 3, neutrophil-specific |
Other Description | defensin 3, neutrophil-specific|neutrophil defensin 3|neutrophil peptide 3 |
Swissprots | P59666 |
Accessions | AAB57722 AAT68881 AAT68885 CAM91150 P59666 BC027917 AAH27917 BC119706 AAI19707 EU176174 ABW03625 M21131 AAA35753 M23281 AAA52304 X13621 CAA31952 XM_011534741 XP_011533043 NM_005217 NP_005208 |
Function | Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. {ECO:0000269|PubMed:15616305, ECO:0000269|PubMed:15894545, ECO:0000269|PubMed:17452329, ECO:0000269|PubMed:2006422}. |
Subcellular Location | Secreted. |
Top Pathways | Transcriptional misregulation in cancer |
DEFA3-Antibody-C-term-Blocking-Peptide - BP19266b from Abgent, a WuXi AppTec company
|
||||||||||
DEFA1/3 precursor blocking peptide - GTX88155-PEP from GeneTex
|
||||||||||
Human DEFa3 Protein - abx066284 from Abbexa
|
||||||||||
Defensin alpha 3 - H00001668-P01-10 from Acris Antibodies
|
||||||||||
Defensin alpha 3 - H00001668-P01-25 from Acris Antibodies
|
||||||||||
Defensin Alpha 3, Neutrophil Specific (DEFa3), Human - 20-8886 from ARP American Research Products
|
||||||||||
DEFA3 fusion protein - ag3879 from Proteintech Group
|
||||||||||
Recombinant Human DEFA3 - DEFA3-701H from Creative Biomart
|
||||||||||
Recombinant Defensin Alpha 3, Neutrophil Specific (DEFa3) - RPE135Hu01 from Uscn Life Science Inc.
|
||||||||||
Recombinant Defensin Alpha 3, Neutrophil Specific (DEFa3) - RPE135Hu02 from Uscn Life Science Inc.
|
||||||||||
Defensin α3 (S52) Peptide - BS3452P from Bioworld Technology
|
||||||||||
Recombinant Defensin Alpha 3, Neutrophil Specific (DEFa3) - RPE135Hu01 from Cloud-clone
|
||||||||||
Recombinant Defensin Alpha 3, Neutrophil Specific (DEFa3) - RPE135Hu02 from Cloud-clone
|
||||||||||
Recombinant Human Neutrophil defensin 3(DEFA3) - CSB-YP006655HU CSB-EP006655HU CSB-BP006655HU CSB-MP006655HU from Cusabio
|
||||||||||
DEFA3 Protein - abx163693 from Abbexa
|
||||||||||
Recombinant Human DEFA3 Protein, Fc-tagged - DEFA3-647H from Creative Biomart
|
||||||||||
Neutrophil defensin 3 - AF1865 from Creative Peptides
|
||||||||||
DEFA3 Recombinant Protein (OPCD02702) - OPCD02702 from Aviva Systems Biology
|
||||||||||
DEFA3 Recombinant Protein (OPCD02703) - OPCD02703 from Aviva Systems Biology
|
||||||||||
Defensin Alpha 3, Recombinant Protein - MBS2031224 from MyBioSource
|
||||||||||
Defensin Alpha 3, Neutrophil Specific (DEFa3), Recombinant Protein - MBS2010173 from MyBioSource
|
||||||||||
Neutrophil defensin 3 (DEFA3), Recombinant Protein - MBS955711 from MyBioSource
|
||||||||||
Recombinant Human DEFA3 Protein (39-94 aa), His-tagged - DEFA3-2596H from Creative Biomart
|