DEFA3

Gene Symbol DEFA3
Entrez Gene 1668
Alt Symbol DEF3, HNP-3, HNP3, HP-3, HP3
Species Human
Gene Type protein-coding
Description defensin, alpha 3, neutrophil-specific
Other Description defensin 3, neutrophil-specific|neutrophil defensin 3|neutrophil peptide 3
Swissprots P59666
Accessions AAB57722 AAT68881 AAT68885 CAM91150 P59666 BC027917 AAH27917 BC119706 AAI19707 EU176174 ABW03625 M21131 AAA35753 M23281 AAA52304 X13621 CAA31952 XM_011534741 XP_011533043 NM_005217 NP_005208
Function Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. {ECO:0000269|PubMed:15616305, ECO:0000269|PubMed:15894545, ECO:0000269|PubMed:17452329, ECO:0000269|PubMed:2006422}.
Subcellular Location Secreted.
Top Pathways Transcriptional misregulation in cancer

HNP-3 CRISPR/Cas9 KO Plasmid (h) - sc-417619 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HNP-3 HDR Plasmid (h) - sc-417619-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HNP-3 Double Nickase Plasmid (h) - sc-417619-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HNP-3 Double Nickase Plasmid (h2) - sc-417619-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HNP-3 CRISPR Activation Plasmid (h) - sc-417619-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HNP-3 CRISPR Activation Plasmid (h2) - sc-417619-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HNP-3 Lentiviral Activation Particles (h) - sc-417619-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HNP-3 Lentiviral Activation Particles (h2) - sc-417619-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HNP-3 siRNA (h) - sc-105533 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HNP-3 shRNA Plasmid (h) - sc-105533-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HNP-3 shRNA (h) Lentiviral Particles - sc-105533-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN7086 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7086 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DEFA3 siRNA (Human) - CRH1177 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DEFA3 - MBS8215032 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human DEFA3 siRNA - orb261679 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DEFA3 shRNA Plasmid (Human) - CHH1177 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DEFA3 miRNA 3'UTR clone - MiUTR3H-06886 from Creative biogene

Species Reactivities Human
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