CREB3L4

Gene Symbol CREB3L4
Entrez Gene 148327
Alt Symbol AIBZIP, ATCE1, CREB3, CREB4, JAL, hJAL
Species Human
Gene Type protein-coding
Description cAMP responsive element binding protein 3-like 4
Other Description CREB-4|androgen-induced basic leucine zipper protein|attaching to CRE-like 1|cAMP responsive element binding protein 1|cAMP-responsive element-binding protein 3-like protein 4|cAMP-responsive element-binding protein 4|cyclic AMP-responsive element-binding protein 3-like protein 4|cyclic AMP-responsive element-binding protein 4|tisp40|transcript induced in spermiogenesis protein 40
Swissprots Q8TEY5 Q5T4L0 Q86YW6 D3DV62
Accessions BAC45224 EAW53251 EAW53252 EAW53253 EAW53254 EAW53255 EAW53256 EAW53257 EAW53258 Q8TEY5 AA652478 AB052778 BAC45035 AF394167 AAL76113 AF468007 AAO33070 AK297703 BAG60061 AK304259 BAG65125 AK304665 BAG65440 AK309767 AY049977 AAL13157 BC038962 AAH38962 BF681098 BX647716 DB012316 EU446885 ABZ92414 EU832796 ACE87807 EU832838 ACE87849 GQ129234 ACT64368 GQ129341 ACT64475 XM_006711172 XP_006711235 NM_001255978 NP_001242907 NM_001255979 NP_001242908 NM_001255980 NP_001242909 NM_001255981 NP_001242910 NM_130898 NP_570968 NR_045658
Function Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements (By similarity). {ECO:0000250}.
Subcellular Location Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Note=May also be located in Golgi apparatus.
Tissue Specificity According to PubMed:11830526, exclusively expressed in the prostate. Expressed in breast and prostate cancer cell lines. Expressed in prostatic luminal epithelial cells (at protein level). Expression is significantly more abundant in prostate cancer than in benign prostatic tissue (prostatic hyperplasia). According to PubMed:12111373, also expressed in brain, pancreas and skeletal muscle, and at lower levels in small intestine, testis, leukocyte and thymus. {ECO:0000269|PubMed:11830526, ECO:0000269|PubMed:12111373, ECO:0000269|PubMed:17270658}.
Top Pathways cGMP-PKG signaling pathway, Huntington's disease, Glucagon signaling pathway, Prostate cancer, PI3K-Akt signaling pathway

CREB3L4 (D-8) - sc-514052 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CREB3L4 (D-8): sc-514052. Western blot analysis of CREB3L4 expression in non-transfected: sc-117752 (A) and human CREB3L4 transfected: sc-115476 (B) 293T whole cell lysates.

CREB3L4 (D-6) - sc-390850 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CREB3L4 (D-6): sc-390850. Western blot analysis of CREB3L4 expression in non-transfected: sc-117752 (A) and human CREB3L4 transfected: sc-115476 (B) 293T whole cell lysates.

CREB3L4 (K-17) - sc-54796 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CREB3L4 (K-17): sc-54796. Western blot analysis of CREB3L4 expression in non-transfected: sc-117752 (A) and human CREB3L4 transfected: sc-115476 (B) 293T whole cell lysates.

CREB3L4 (H-115) - sc-366619 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CREB3L4 (H-115): sc-366619. Western blot analysis of CREB3L4 expression in CSMLO (A), NIH/3T3 (B) and Neuro-2A (C) whole cell lysates and mouse placenta tissue extract (D).

CREB3L4 (M-180) - sc-366620 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CREB3L4 (M-180): sc-366620. Western blot analysis of CREB3L4 expression in non-transfected: sc-117752 (A) and human CREB3L4 transfected: sc-115476 (B) 293T whole cell lysates.

CREB3L4 (Y-18) - sc-54801 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-AIBZIP antibody - ab115466 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
ab115466, at 5 µg/ml, staining AIBZIP in formalin fixed, paraffin embedded Human prostate tissue by Immunohistochemistry.

Anti-AIBZIP antibody - ab2474 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-AIBZIP antibody (ab2474) at 0.5 µg/ml + Human placental lysates at 35 µgdeveloped using the ECL technique

Anti-AIBZIP antibody - ab84310 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-AIBZIP antibody (ab84310) at 1/200 dilutionLane 1 : A549 cell lysateLane 2 : Fetal liver lysateLane 3 : A549 cell lysate with blocking peptideLane 4 : Fetal liver lysate with blocking peptide

Anti-AIBZIP antibody - ab130724 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-AIBZIP antibody (ab130724) at 1/100 dilution + A375 cell lysate at 35 µg

Anti-AIBZIP antibody - ab58366 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab58366 AIBZIP antibody at 1ug/ml.

Anti-AIBZIP antibody [1165CT161.1] - ab188363 from Abcam

Prices $370.00
Sizes 400 µl
Host Mouse
Clonality Monoclonal
Clone 1165CT161.1
All lanes : Anti-AIBZIP antibody [1165CT161.1] (ab188363) at 1/1000 dilutionLane 1 : Daudi cell lysateLane 2 : PC3 cell lysateLane 3 : MCF7 cell lysateLane 4 : C6 cell lysateLane 5 : L6 cell lysateLane 6 : Rat brain tissue lysateLysates/proteins at 35 µg per lane.developed using the ECL technique

Anti-AIBZIP antibody [EPR7382] - ab151736 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7382
All lanes : Anti-AIBZIP antibody [EPR7382] (ab151736) at 1/1000 dilutionLane 1 : Human prostate cancer lysateLane 2 : Human breast cancer lysateLane 3 : PC3 cell lysateLane 4 : LnCaP cell lysateLane 5 : MCF7 cell lysateLane 6 : T47D cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-CREB3L4 / AIBZIP Antibody (C-Terminus) IHC-plus™ - LS-B2272 from LifeSpan Bioscience

Host Goat
Clonality Polyclonal
Anti-CREB3L4 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2272 concentration 5 ug/ml.

Anti-CREB3L4 / AIBZIP Antibody (aa1-395) - LS-C126595 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CREB3L4 / AIBZIP Antibody (aa337-366, AP) - LS-C234230 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CREB3L4 / AIBZIP Antibody (aa337-366, APC) - LS-C234231 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CREB3L4 / AIBZIP Antibody (aa337-366, Biotin) - LS-C234232 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CREB3L4 / AIBZIP Antibody (aa337-366, FITC) - LS-C234233 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CREB3L4 / AIBZIP Antibody (aa337-366, PE) - LS-C234234 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CREB3L4 / AIBZIP Antibody (aa337-366, Azide-free, HRP) - LS-C249753 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CREB3L4 / AIBZIP Antibody (aa1-111) - LS-C307082 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CREB3L4 / AIBZIP Antibody (aa337-366) - LS-C320585 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CREB3L4 / AIBZIP Antibody (C-Terminus) - LS-C178860 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CREB3L4 / AIBZIP Antibody (aa1-300, clone 1165CT16.1.1) - LS-C344118 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 1165CT16.1.1
CREB3L4 Antibody (M01) western blot of Daudi, PC-3, MCF-7, rat C6 and L6 cell line , rat brain tissue lysates (35 ug/lane). The CREB3L4 (M01)antibody detected the CREB3L4 (M01)protein (arrow).
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