CREB3L4

Gene Symbol	CREB3L4
Entrez Gene	148327
Alt Symbol	AIBZIP, ATCE1, CREB3, CREB4, JAL, hJAL
Species	Human
Gene Type	protein-coding
Description	cAMP responsive element binding protein 3-like 4
Other Description	CREB-4|androgen-induced basic leucine zipper protein|attaching to CRE-like 1|cAMP responsive element binding protein 1|cAMP-responsive element-binding protein 3-like protein 4|cAMP-responsive element-binding protein 4|cyclic AMP-responsive element-binding protein 3-like protein 4|cyclic AMP-responsive element-binding protein 4|tisp40|transcript induced in spermiogenesis protein 40
Swissprots	Q8TEY5 Q5T4L0 Q86YW6 D3DV62
Accessions	BAC45224 EAW53251 EAW53252 EAW53253 EAW53254 EAW53255 EAW53256 EAW53257 EAW53258 Q8TEY5 AA652478 AB052778 BAC45035 AF394167 AAL76113 AF468007 AAO33070 AK297703 BAG60061 AK304259 BAG65125 AK304665 BAG65440 AK309767 AY049977 AAL13157 BC038962 AAH38962 BF681098 BX647716 DB012316 EU446885 ABZ92414 EU832796 ACE87807 EU832838 ACE87849 GQ129234 ACT64368 GQ129341 ACT64475 XM_006711172 XP_006711235 NM_001255978 NP_001242907 NM_001255979 NP_001242908 NM_001255980 NP_001242909 NM_001255981 NP_001242910 NM_130898 NP_570968 NR_045658
Function	Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements (By similarity). {ECO:0000250}.
Subcellular Location	Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. Note=May also be located in Golgi apparatus.
Tissue Specificity	According to PubMed:11830526, exclusively expressed in the prostate. Expressed in breast and prostate cancer cell lines. Expressed in prostatic luminal epithelial cells (at protein level). Expression is significantly more abundant in prostate cancer than in benign prostatic tissue (prostatic hyperplasia). According to PubMed:12111373, also expressed in brain, pancreas and skeletal muscle, and at lower levels in small intestine, testis, leukocyte and thymus. {ECO:0000269|PubMed:11830526, ECO:0000269|PubMed:12111373, ECO:0000269|PubMed:17270658}.
Top Pathways	cGMP-PKG signaling pathway, Huntington's disease, Glucagon signaling pathway, Prostate cancer, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CREB3L4 CRISPR/Cas9 KO Plasmid (h) - sc-417626 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CREB3L4 HDR Plasmid (h) - sc-417626-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CREB3L4 Double Nickase Plasmid (h) - sc-417626-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CREB3L4 Double Nickase Plasmid (h2) - sc-417626-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CREB3L4 CRISPR Activation Plasmid (h) - sc-417626-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CREB3L4 CRISPR Activation Plasmid (h2) - sc-417626-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

CREB3L4 Lentiviral Activation Particles (h) - sc-417626-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CREB3L4 Lentiviral Activation Particles (h2) - sc-417626-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

CREB3L4 siRNA (h) - sc-62158 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CREB3L4 shRNA Plasmid (h) - sc-62158-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CREB3L4 shRNA (h) Lentiviral Particles - sc-62158-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

CREB3 RNAi - H00010488-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

AIBZIP RNAi - H00148327-R01V from Novus Biologicals Category siRNA Prices $629.00 Sizes 20 nmol Species Reactivities Human

AIBZIP RNAi - H00148327-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU156841 from Sigma-Aldrich Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN6556 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6556 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

CREB3L4 siRNA (Human) - CRJ5580 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CREB3L4 - MBS8220929 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human CREB3L4 (NM_130898.3) - SHH269345 from Creative biogene Category siRNA Species Reactivities Human

Human CREB3L4 siRNA - orb276081 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

CREB3L4 shRNA Plasmid (Human) - CHJ5580 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

CREB3L4 miRNA 3'UTR clone - MiUTR3H-08997 from Creative biogene Species Reactivities Human

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