Gene Symbol | TXNDC5 |
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Entrez Gene | 81567 |
Alt Symbol | ENDOPDI, ERP46, HCC-2, PDIA15, STRF8, UNQ364 |
Species | Human |
Gene Type | protein-coding |
Description | thioredoxin domain containing 5 (endoplasmic reticulum) |
Other Description | ER protein 46|endoplasmic reticulum protein ERp46|endoplasmic reticulum resident protein 46|endothelial protein disulphide isomerase|protein disulfide isomerase family A, member 15|thioredoxin domain-containing protein 5|thioredoxin related protein|thioredoxin-like protein p46 |
Swissprots | Q5TCQ0 Q8NBS9 Q9BVH9 Q8ND33 B2RDM2 Q8TCT2 |
Accessions | EAW55220 EAW55221 EAW55222 Q8NBS9 AJ440721 CAD29430 AK025006 AK075291 BAC11526 AK098089 AK315598 BAG37969 AL833008 CAH56286 AL834423 CAD39084 AY326464 AAR99514 AY358646 AAQ89009 BC001199 AAH01199 BC003529 BF726049 BU855393 NM_001145549 NP_001139021 NM_030810 NP_110437 NM_022085 |
Function | Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide- isomerase deficiency in yeast (By similarity). {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}. |
Top Pathways | Protein processing in endoplasmic reticulum |
ERp46 (C-11) - sc-271667 from Santa Cruz Biotechnology
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ERp46 (C-15) - sc-49659 from Santa Cruz Biotechnology
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ERp46 (F-3) - sc-271465 from Santa Cruz Biotechnology
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ERp46 (E-19) - sc-49660 from Santa Cruz Biotechnology
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ERp46 (H-80) - sc-134829 from Santa Cruz Biotechnology
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Anti-TXNDC5 antibody - ab13820 from Abcam
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Anti-TXNDC5 antibody - ab88506 from Abcam
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Anti-TXNDC5 antibody - ab173936 from Abcam
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Anti-TXNDC5 antibody - ab84665 from Abcam
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Anti-TXNDC5 antibody [2E7/7] - ab174639 from Abcam
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Anti-TXNDC5 / ERP46 Antibody (C-Terminus) IHC-plus™ - LS-B9189 from LifeSpan Bioscience
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Anti-TXNDC5 / ERP46 Antibody (clone 1C3) - LS-C338449 from LifeSpan Bioscience
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Anti-TXNDC5 / ERP46 Antibody (Internal) IHC-plus™ - LS-B9233 from LifeSpan Bioscience
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Anti-TXNDC5 / ERP46 Antibody (aa52-63, clone 2E7/7) - LS-C209620 from LifeSpan Bioscience
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Anti-TXNDC5 / ERP46 Antibody (aa126-155, APC) - LS-C218224 from LifeSpan Bioscience
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Anti-TXNDC5 / ERP46 Antibody (aa126-155, AP) - LS-C218225 from LifeSpan Bioscience
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Anti-TXNDC5 / ERP46 Antibody (aa126-155, Biotin) - LS-C218226 from LifeSpan Bioscience
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Anti-TXNDC5 / ERP46 Antibody (aa126-155, FITC) - LS-C218227 from LifeSpan Bioscience
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Anti-TXNDC5 / ERP46 Antibody (aa126-155, Azide-free, HRP) - LS-C218228 from LifeSpan Bioscience
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Anti-TXNDC5 / ERP46 Antibody (aa126-155, PE) - LS-C218231 from LifeSpan Bioscience
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Anti-TXNDC5 / ERP46 Antibody (aa36-85) - LS-C102798 from LifeSpan Bioscience
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Anti-TXNDC5 / ERP46 Antibody (aa52-63, clone 2E7/7, Atto 565) - LS-C230348 from LifeSpan Bioscience
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Anti-TXNDC5 / ERP46 Antibody (aa52-63, clone 2E7/7, Atto 488) - LS-C230350 from LifeSpan Bioscience
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Anti-TXNDC5 / ERP46 Antibody (aa52-63, clone 2E7/7, Atto 594) - LS-C230349 from LifeSpan Bioscience
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Anti-TXNDC5 / ERP46 Antibody (aa52-63, clone 2E7/7, Atto 633) - LS-C230351 from LifeSpan Bioscience
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