Gene Symbol | TXNDC5 |
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Entrez Gene | 81567 |
Alt Symbol | ENDOPDI, ERP46, HCC-2, PDIA15, STRF8, UNQ364 |
Species | Human |
Gene Type | protein-coding |
Description | thioredoxin domain containing 5 (endoplasmic reticulum) |
Other Description | ER protein 46|endoplasmic reticulum protein ERp46|endoplasmic reticulum resident protein 46|endothelial protein disulphide isomerase|protein disulfide isomerase family A, member 15|thioredoxin domain-containing protein 5|thioredoxin related protein|thioredoxin-like protein p46 |
Swissprots | Q5TCQ0 Q8NBS9 Q9BVH9 Q8ND33 B2RDM2 Q8TCT2 |
Accessions | EAW55220 EAW55221 EAW55222 Q8NBS9 AJ440721 CAD29430 AK025006 AK075291 BAC11526 AK098089 AK315598 BAG37969 AL833008 CAH56286 AL834423 CAD39084 AY326464 AAR99514 AY358646 AAQ89009 BC001199 AAH01199 BC003529 BF726049 BU855393 NM_001145549 NP_001139021 NM_030810 NP_110437 NM_022085 |
Function | Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide- isomerase deficiency in yeast (By similarity). {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}. |
Top Pathways | Protein processing in endoplasmic reticulum |
ERp46 CRISPR/Cas9 KO Plasmid (h) - sc-402661 from Santa Cruz Biotechnology
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ERp46 HDR Plasmid (h) - sc-402661-HDR from Santa Cruz Biotechnology
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ERp46 Double Nickase Plasmid (h) - sc-402661-NIC from Santa Cruz Biotechnology
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ERp46 Double Nickase Plasmid (h2) - sc-402661-NIC-2 from Santa Cruz Biotechnology
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ERp46 CRISPR Activation Plasmid (h) - sc-402661-ACT from Santa Cruz Biotechnology
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ERp46 CRISPR Activation Plasmid (h2) - sc-402661-ACT-2 from Santa Cruz Biotechnology
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ERp46 Lentiviral Activation Particles (h) - sc-402661-LAC from Santa Cruz Biotechnology
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ERp46 Lentiviral Activation Particles (h2) - sc-402661-LAC-2 from Santa Cruz Biotechnology
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ERp46 siRNA (h) - sc-60601 from Santa Cruz Biotechnology
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ERp46 shRNA Plasmid (h) - sc-60601-SH from Santa Cruz Biotechnology
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ERp46 shRNA (h) Lentiviral Particles - sc-60601-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN22309 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22309 from Sigma-Aldrich
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TXNDC5 siRNA (Human) - CRJ3003 from Cohesion Biosciences
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TXNDC5 - MBS8228961 from MyBioSource
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shRNA set against Human TXNDC5 (NM_001145549.2) - SHH438284 from Creative biogene
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TXNDC5 shRNA Plasmid (Human) - CHJ3003 from Cohesion Biosciences
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TXNDC5 miRNA 3'UTR clone - MiUTR3H-16485 from Creative biogene
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TXNDC5 miRNA 3'UTR clone - MiUTR3H-16486 from Creative biogene
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