| Gene Symbol |
TXNDC5
|
| Entrez Gene |
81567
|
| Alt Symbol |
ENDOPDI, ERP46, HCC-2, PDIA15, STRF8, UNQ364
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
thioredoxin domain containing 5 (endoplasmic reticulum)
|
| Other Description |
ER protein 46|endoplasmic reticulum protein ERp46|endoplasmic reticulum resident protein 46|endothelial protein disulphide isomerase|protein disulfide isomerase family A, member 15|thioredoxin domain-containing protein 5|thioredoxin related protein|thioredoxin-like protein p46
|
| Swissprots |
Q5TCQ0 Q8NBS9 Q9BVH9 Q8ND33 B2RDM2 Q8TCT2
|
| Accessions |
EAW55220 EAW55221 EAW55222 Q8NBS9 AJ440721 CAD29430 AK025006 AK075291 BAC11526 AK098089 AK315598 BAG37969 AL833008 CAH56286 AL834423 CAD39084 AY326464 AAR99514 AY358646 AAQ89009 BC001199 AAH01199 BC003529 BF726049 BU855393 NM_001145549 NP_001139021 NM_030810 NP_110437 NM_022085
|
| Function |
Possesses thioredoxin activity. Has been shown to reduce insulin disulfide bonds. Also complements protein disulfide- isomerase deficiency in yeast (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}.
|
| Top Pathways |
Protein processing in endoplasmic reticulum
|
![Western Blot: TXNDC5 Overexpression Lysate (Adult Normal) [NBL1-17472] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TXNDC5.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5178_TXNDC5%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17472-img0001.jpg)