Gene Symbol | Lamtor4 |
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Entrez Gene | 66096 |
Alt Symbol | 0910001L09Rik, AV006840 |
Species | Mouse |
Gene Type | protein-coding |
Description | late endosomal/lysosomal adaptor, MAPK and MTOR activator 4 |
Other Description | UPF0539 protein C7orf59 homolog|late endosomal/lysosomal adaptor and MAPK and MTOR activator 4|ragulator complex protein LAMTOR4 |
Swissprots | Q8CF77 B7ZN18 Q8CF66 Q8CEW4 |
Accessions | Q8CF66 AK002488 BAC24993 AK003086 BAC25020 AK003250 AK010598 BAC25306 AK146994 BC056178 BC144958 AAI44959 NM_001081108 NP_001074577 |
Function | As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated (By similarity). {ECO:0000250}. |
Subcellular Location | Lysosome {ECO:0000250}. |
Anti-LAMTOR4 Antibody (N-Terminus) - LS-C146520 from LifeSpan Bioscience
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C7orf59 Antibody - NBP1-98263 from Novus Biologicals
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Anti-Lamtor4 antibody produced in rabbit - SAB2107058 from Sigma-Aldrich
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0910001L09Rik antibody - N-terminal region (ARP54397_P050) - ARP54397_P050 from Aviva Systems Biology
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0910001L09Rik Antibody - GWB-MT364D from Genway Biotech
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Anti-LAMTOR4 (aa 1-50) polyclonal antibody - DPABH-28436 from Creative Diagnostics
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0910001L09Rik-antibody-N-terminal-region-AI13641 - AI13641 from Abgent, a WuXi AppTec company
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Lamtor4 antibody - orb325912 from Biorbyt
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Anti-0910001L09Rik Antibody A12648 - A12648 from Boster Bio
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0910001L09Rik antibody - N-terminal region : Biotin (ARP54397_P050-Biotin) - ARP54397_P050-Biotin from Aviva Systems Biology
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0910001L09Rik antibody - N-terminal region : FITC (ARP54397_P050-FITC) - ARP54397_P050-FITC from Aviva Systems Biology
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0910001L09Rik antibody - N-terminal region : HRP (ARP54397_P050-HRP) - ARP54397_P050-HRP from Aviva Systems Biology
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Anti-LAMTOR4 Antibody (N-Terminus, Biotin) - LS-C458514 from LifeSpan Bioscience
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Anti-LAMTOR4 Antibody (N-Terminus, HRP) - LS-C458516 from LifeSpan Bioscience
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Anti-LAMTOR4 Antibody (N-Terminus, FITC) - LS-C458515 from LifeSpan Bioscience
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