Gene Symbol | TTYH2 |
---|---|
Entrez Gene | 94015 |
Alt Symbol | C17orf29 |
Species | Human |
Gene Type | protein-coding |
Description | tweety family member 2 |
Other Description | hTTY2|protein tweety homolog 2|tweety homolog 2 |
Swissprots | Q9BSA4 Q96PK1 Q8NBB7 Q3B7H8 B3KX97 Q3B7R9 Q6AWB4 |
Accessions | CCQ43804 EAW89142 EAW89143 Q9BSA4 AF319952 AAL16784 AK058197 AK091085 BAC03579 AK126955 BAG54409 AK296511 BAG59143 AK315163 BAG37607 AL831858 CAD38555 BC004233 BC005168 AAH05168 BC107492 AAI07493 BC107602 AAI07603 BF529231 BX647912 CAH10576 XM_005257824 XP_005257881 NM_032646 NP_116035 NM_052869 NP_443101 |
Function | Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation. {ECO:0000269|PubMed:15010458}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Expressed at higher level in brain and testis and at lower levels in heart, ovary, spleen and peripheral blood leukocytes. Up-regulated in 13 of 16 renal cell carcinoma samples examined. Up-regulated in colon carcinoma. {ECO:0000269|PubMed:11597145, ECO:0000269|PubMed:17569141}. |