| Gene Symbol |
TTYH2
|
| Entrez Gene |
94015
|
| Alt Symbol |
C17orf29
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tweety family member 2
|
| Other Description |
hTTY2|protein tweety homolog 2|tweety homolog 2
|
| Swissprots |
Q9BSA4 Q96PK1 Q8NBB7 Q3B7H8 B3KX97 Q3B7R9 Q6AWB4
|
| Accessions |
CCQ43804 EAW89142 EAW89143 Q9BSA4 AF319952 AAL16784 AK058197 AK091085 BAC03579 AK126955 BAG54409 AK296511 BAG59143 AK315163 BAG37607 AL831858 CAD38555 BC004233 BC005168 AAH05168 BC107492 AAI07493 BC107602 AAI07603 BF529231 BX647912 CAH10576 XM_005257824 XP_005257881 NM_032646 NP_116035 NM_052869 NP_443101
|
| Function |
Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation. {ECO:0000269|PubMed:15010458}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Expressed at higher level in brain and testis and at lower levels in heart, ovary, spleen and peripheral blood leukocytes. Up-regulated in 13 of 16 renal cell carcinoma samples examined. Up-regulated in colon carcinoma. {ECO:0000269|PubMed:11597145, ECO:0000269|PubMed:17569141}.
|