Gene Symbol | TTYH2 |
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Entrez Gene | 94015 |
Alt Symbol | C17orf29 |
Species | Human |
Gene Type | protein-coding |
Description | tweety family member 2 |
Other Description | hTTY2|protein tweety homolog 2|tweety homolog 2 |
Swissprots | Q9BSA4 Q96PK1 Q8NBB7 Q3B7H8 B3KX97 Q3B7R9 Q6AWB4 |
Accessions | CCQ43804 EAW89142 EAW89143 Q9BSA4 AF319952 AAL16784 AK058197 AK091085 BAC03579 AK126955 BAG54409 AK296511 BAG59143 AK315163 BAG37607 AL831858 CAD38555 BC004233 BC005168 AAH05168 BC107492 AAI07493 BC107602 AAI07603 BF529231 BX647912 CAH10576 XM_005257824 XP_005257881 NM_032646 NP_116035 NM_052869 NP_443101 |
Function | Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation. {ECO:0000269|PubMed:15010458}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Expressed at higher level in brain and testis and at lower levels in heart, ovary, spleen and peripheral blood leukocytes. Up-regulated in 13 of 16 renal cell carcinoma samples examined. Up-regulated in colon carcinoma. {ECO:0000269|PubMed:11597145, ECO:0000269|PubMed:17569141}. |
TTYH2 CRISPR/Cas9 KO Plasmid (h) - sc-413987 from Santa Cruz Biotechnology
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TTYH2 HDR Plasmid (h) - sc-413987-HDR from Santa Cruz Biotechnology
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TTYH2 Double Nickase Plasmid (h) - sc-413987-NIC from Santa Cruz Biotechnology
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TTYH2 Double Nickase Plasmid (h2) - sc-413987-NIC-2 from Santa Cruz Biotechnology
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TTYH2 CRISPR Activation Plasmid (h) - sc-413987-ACT from Santa Cruz Biotechnology
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TTYH2 CRISPR Activation Plasmid (h2) - sc-413987-ACT-2 from Santa Cruz Biotechnology
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TTYH2 Lentiviral Activation Particles (h) - sc-413987-LAC from Santa Cruz Biotechnology
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TTYH2 Lentiviral Activation Particles (h2) - sc-413987-LAC-2 from Santa Cruz Biotechnology
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TTYH2 siRNA (h) - sc-93961 from Santa Cruz Biotechnology
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TTYH2 shRNA Plasmid (h) - sc-93961-SH from Santa Cruz Biotechnology
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TTYH2 shRNA (h) Lentiviral Particles - sc-93961-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU026351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22249 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22249 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR10483 from Sigma-Aldrich
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TTYH2 siRNA (Human) - CRJ4235 from Cohesion Biosciences
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TTYH2 - MBS8236693 from MyBioSource
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shRNA set against Human TTYH2 (NM_032646.5) - SHH437548 from Creative biogene
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shRNA set against Human TTYH2(NM_052869.1) - SHL105816 from Creative biogene
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shRNA set against Human TTYH2(NM_032646.5) - SHL105884 from Creative biogene
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TTYH2 shRNA Plasmid (Human) - CHJ4235 from Cohesion Biosciences
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TTYH2 miRNA 3'UTR clone - MiUTR1H-10868 from Creative biogene
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TTYH2 miRNA 3'UTR clone - MiUTR1H-10869 from Creative biogene
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