CARD9

Gene Symbol CARD9
Entrez Gene 64170
Alt Symbol CANDF2, hCARD9
Species Human
Gene Type protein-coding
Description caspase recruitment domain family, member 9
Other Description caspase recruitment domain-containing protein 9
Swissprots Q5SXM6 Q5SXM5 Q9H854 Q9H257
Accessions EAW88219 EAW88220 EAW88221 EAW88222 EAW88223 EAW88224 Q9H257 AF311287 AAG28790 AK024001 BAB14766 AK127481 AK292081 BAF84770 AK295647 BAG58517 AK309043 BC008877 AAH08877 BC035805 BI524042 BM148244 DQ893526 ABM84452 EU176781 ABW03582 NM_052813 NP_434700 NM_052814 NP_434701
Function Adapter protein that plays a key role in innate immune response to a number of intracellular pathogens, such as C.albicans and L.monocytogenes. Is at the crossroads of ITAM- tyrosine kinase and the Toll-like receptors (TLR) and NOD2 signaling pathways. Probably controls various innate immune response pathways depending on the intracellular pathogen. In response to L.monocytogenes infection, acts by connecting NOD2 recognition of peptidoglycan to downstream activation of MAP kinases (MAPK) without activating NF-kappa-B. Also involved in activation of myeloid cells via classical ITAM-associated receptors and TLR: required for TLR-mediated activation of MAPK, while it is not required for TLR-induced activation of NF-kappa-B (By similarity). Controls CLEC7A (dectin-1)-mediated myeloid cell activation induced by the yeast cell wall component zymosan, leading to cytokine production and innate anti-fungal immunity: acts by regulating BCL10-MALT1-mediated NF-kappa-B activation pathway. Activat
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11053425}.
Tissue Specificity Highly expressed in spleen. Also detected in liver, placenta, lung, peripheral blood leukocytes and in brain.
Top Pathways NOD-like receptor signaling pathway, Tuberculosis

CARD9 Antibody - 12416 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from THP-1, U-937, and MUTZ-3 cells using CARD9 Antibody.

CARD9 Antibody (Mouse Preferred) - 12283 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from Raw 264.7 and JAWSII cells using CARD9 Antibody (Mouse Preferred).

CARD 9 (C-17) - sc-49405 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CARD 9 (C-17): sc-49405. Western blot analysis of CARD 9 expression in non-transfected 293: sc-110760 (A), human CARD 9 transfected 293: sc-174094 (B) and K-562 (C) whole cell lysates.

CARD 9 (A-8) - sc-374569 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CARD 9 (A-8): sc-374569. Western blot analysis of CARD 9 expression in non-transfected: sc-110760 (A) and human CARD 9 transfected: sc-174094 (B) 293 whole cell lysates.

CARD 9 (H-90) - sc-99054 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CARD 9 (H-90): sc-99054. Western blot analysis of CARD 9 expression in THP-1 whole cell lysate.

CARD 9 (C-2) - sc-374007 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CARD 9 (C-2): sc-374007. Western blot analysis of CARD 9 expression in non-transfected: sc-117760 (A) and human CARD 9 transfected: sc-174094 (B) 293 whole cell lysates.

CARD 9 (F-4) - sc-365545 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CARD 9 (F-4): sc-365545. Western blot analysis of CARD 9 expression in non-transfected: sc-110760 (A) and human CARD 9 transfected: sc-174094 (B) 293 whole cell lysates.

CARD 9 (T-17) - sc-49408 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CARD 9 (T-17): sc-49408. Western blot analysis of CARD 9 expression in non-transfected: sc-110760 (A) and human CARD 9 transfected: sc-174094 (B) 293 whole cell lysates.

Anti-CARD9 antibody - ab155166 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CARD9 antibody (ab155166) at 1/1000 dilution + Raji whole cell lysate at 30 µg

Anti-CARD9 antibody - ab115578 from Abcam

Prices $378.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab115578, at 10µg/ml, staining CARD9 in Formalin-fixed, Paraffin-embedded Human Adrenal tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-CARD9 antibody - ab9649 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of CARD9 expression in human MDA-MB-361 (A) and PC-3 (B) cell lysate with anti-CARD9 at 2.5 µg /ml.

Anti-CARD9 antibody - ab169623 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-CARD9 antibody (ab169623) at 1 µg/mlLane 1 : CARD9 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-CARD9 antibody - ab55950 from Abcam

Prices $372.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CARD9 antibody [EPR6488] - ab124922 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6488
All lanes : Anti-CARD9 antibody [EPR6488] (ab124922) at 1/1000 dilutionLane 1 : THP1 cell lysateLane 2 : Raji cell lysateLane 3 : Jurkat cell lysateLane 4 : PC3 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-CARD9 antibody [EPR6489] - ab133560 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6489
All lanes : Anti-CARD9 antibody [EPR6489] (ab133560) at 1/1000 dilutionLane 1 : K562 cell lysateLane 2 : U937 cell lysateLane 3 : HL60 cell lysateLane 4 : HepG2 cell lysateLane 5 : THP1 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-CARD9 Antibody (N-Terminus) - LS-C46821 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CARD9 Antibody (aa521-536) - LS-C82960 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CARD9 Antibody (aa23-52, Biotin) - LS-C253390 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CARD9 Antibody (aa23-52, APC) - LS-C253389 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CARD9 Antibody (aa23-52, AP) - LS-C253388 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CARD9 Antibody (aa23-52, Azide-free, HRP) - LS-C253393 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CARD9 Antibody (aa23-52, FITC) - LS-C253391 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CARD9 Antibody (aa23-52, PE) - LS-C253394 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CARD9 Antibody (aa467-516) - LS-C116740 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CARD9 antibody LS-C116740 Western blot of Fetal Brain lysate.

Anti-CARD9 Antibody (Internal, clone EPR6489) - LS-C138866 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6489
Western blot analysis on (A) K562, (B) U937, (C) HL-60, (D) HepG2, and (E) THP-1 cell lysates using anti-CARD9 antibody.
Search more