SLC8A3

Gene Symbol SLC8A3
Entrez Gene 6547
Alt Symbol NCX3
Species Human
Gene Type protein-coding
Description solute carrier family 8 (sodium/calcium exchanger), member 3
Other Description Na(+)/Ca(2+)-exchange protein 3|Na+/Ca2+ exchanger 3|sodium/calcium exchanger 3|sodium/calcium exchanger SLC8A3|solute carrier family 8 (sodium-calcium exchanger), member 3|solute carrier family 8 member 3
Swissprots Q5K3P6 Q96QG1 Q8IUE9 Q5K3P7 Q8NFI7 Q96QG2 Q8IUF0 P57103
Accessions AAM90955 CCQ43930 EAW81018 EAW81019 EAW81020 EAW81021 EAW81022 EAW81023 EAW81024 EAW81025 EAW81026 P57103 AF510501 AAN60790 AF510502 AAN60791 AF510503 AAN60792 AJ304852 CAC40984 AJ304853 CAC40985 AJ508602 CAD48420 AJ745101 CAG33739 AJ745102 CAG33740 AK096553 BAG53321 AK122728 BAG53692 BC023215 BC036783 BC114217 BC142969 AAI42970 BC150183 AAI50184 BC150193 AAI50194 BC160014 AAI60014 BI551720 BI906774 BX098112 BX248763 CAD66570 DA351808 XM_005268017 XP_005268074 XM_005268018 XP_005268075 XM_006720240 XP_006720303 XM_011537101 XP_011535403 XM_011537102 XP_011535404 NM_001130417 NP_001123889 NM_033262 NP_150287 NM_058240 NP_489479 NM_182932 NP_891977 NM_182936 NP_891981 NM_183002 NP_892114 NR_104122 NM_182933
Function Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Isoform 2 is expressed in brain and skeletal muscle. Isoform 3 is expressed in excitable cells of brain, retina and skeletal muscle. Isoform 4 is expressed in skeletal muscle. {ECO:0000269|PubMed:15777725}.
Top Pathways Calcium signaling pathway, Protein digestion and absorption, cGMP-PKG signaling pathway

SLC8A3 overexpression lysate - LY409219 from Acris Antibodies

Category Cell Lysate
Prices $480.00
Sizes 100 µg

Sodium-Calcium Exchanger Overexpression Lysate (Native) - NBP2-05794 from Novus Biologicals

Category Cell Lysate
Prices $529.00
Sizes 100 µg
Western Blot: Sodium-Calcium Exchanger Overexpression Lysate (Adult Normal) [NBP2-05794] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Sodium-Calcium Exchanger.

Panoply™ Human SLC8A3 Knockdown Stable Cell Line - CSC-DC014655 from Creative biogene

Category Cell Line
Species Human
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