SLC8A3

Gene Symbol SLC8A3
Entrez Gene 6547
Alt Symbol NCX3
Species Human
Gene Type protein-coding
Description solute carrier family 8 (sodium/calcium exchanger), member 3
Other Description Na(+)/Ca(2+)-exchange protein 3|Na+/Ca2+ exchanger 3|sodium/calcium exchanger 3|sodium/calcium exchanger SLC8A3|solute carrier family 8 (sodium-calcium exchanger), member 3|solute carrier family 8 member 3
Swissprots Q5K3P6 Q96QG1 Q8IUE9 Q5K3P7 Q8NFI7 Q96QG2 Q8IUF0 P57103
Accessions AAM90955 CCQ43930 EAW81018 EAW81019 EAW81020 EAW81021 EAW81022 EAW81023 EAW81024 EAW81025 EAW81026 P57103 AF510501 AAN60790 AF510502 AAN60791 AF510503 AAN60792 AJ304852 CAC40984 AJ304853 CAC40985 AJ508602 CAD48420 AJ745101 CAG33739 AJ745102 CAG33740 AK096553 BAG53321 AK122728 BAG53692 BC023215 BC036783 BC114217 BC142969 AAI42970 BC150183 AAI50184 BC150193 AAI50194 BC160014 AAI60014 BI551720 BI906774 BX098112 BX248763 CAD66570 DA351808 XM_005268017 XP_005268074 XM_005268018 XP_005268075 XM_006720240 XP_006720303 XM_011537101 XP_011535403 XM_011537102 XP_011535404 NM_001130417 NP_001123889 NM_033262 NP_150287 NM_058240 NP_489479 NM_182932 NP_891977 NM_182936 NP_891981 NM_183002 NP_892114 NR_104122 NM_182933
Function Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Isoform 2 is expressed in brain and skeletal muscle. Isoform 3 is expressed in excitable cells of brain, retina and skeletal muscle. Isoform 4 is expressed in skeletal muscle. {ECO:0000269|PubMed:15777725}.
Top Pathways Calcium signaling pathway, Protein digestion and absorption, cGMP-PKG signaling pathway

NCX3 (C-15) - sc-48896 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NCX3 (C-15): sc-48896. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic staining of glandular cells.

NCX3 (H-60) - sc-368340 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
NCX3 (H-60): sc-368340. Western blot analysis of NCX3 expression in U-251-MG (A), Sol8 (B) and PC-12 (C) whole cell lysates and mouse skeletal muscle (D) and rat brain (E) tissue extracts.

Anti-SLC8A3 antibody - ab84708 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SLC8A3 antibody (ab84708) at 1 µg/ml (in 5% skim milk / PBS buffer) + 721_B cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-SLC8A3 antibody - C-terminal - ab170763 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of formalin fixed and paraffin embedded Human brain tissue labeling SLC8A3 with ab170763 at 1/10 dilution, followed by peroxidase conjugation of the secondary antibody and DAB staining.

Anti-SLC8A3 / NCX3 Antibody (N-Terminus) - LS-C16745 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC8A3 / NCX3 Antibody (N-Terminus) - LS-C16744 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC8A3 / NCX3 Antibody (aa609-622) - LS-C154997 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-SLC8A3 / NCX3 Antibody (aa27-40) - LS-C154996 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-SLC8A3 / NCX3 Antibody (aa585-614, APC) - LS-C240958 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC8A3 / NCX3 Antibody (aa585-614, AP) - LS-C240959 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC8A3 / NCX3 Antibody (aa585-614, FITC) - LS-C240960 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC8A3 / NCX3 Antibody (aa585-614, Biotin) - LS-C240961 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC8A3 / NCX3 Antibody (aa585-614, PE) - LS-C240966 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC8A3 / NCX3 Antibody (aa585-614, Azide-free, HRP) - LS-C248194 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC8A3 / NCX3 Antibody (aa592-622) - LS-C325177 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC8A3 / NCX3 Antibody (aa585-614) - LS-C161278 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SLC8A3 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-SLC8A3 / NCX3 Antibody (aa144-193) IHC-plus™ - LS-B5775 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SLC8A3 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5775 concentration 5 ug/ml.

Sodium-Calcium Exchanger Antibody (C2C12) - NB120-2869 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone C2C12
Immunocytochemistry/Immunofluorescence: Sodium-Calcium Exchanger Antibody (C2C12) [NB120-2869] - Sodium/Calcium Exchanger staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with or an antibody recognizing Sodium/Calcium Exchanger at a dilution of 1:100 over night at 4C, washed with PBS and incubated with a DyLight-488 conjugated.

Sodium-Calcium Exchanger Antibody - NBP1-69515 from Novus Biologicals

Prices $369.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: sodium-calcium exchanger Antibody [NBP1-69515] - This Anti-SLC8A3 antibody was used in Western Blot of 721_B tissue lysate at a concentration of 1ug/ml.

Sodium-Calcium Exchanger Antibody - NBP1-87808 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Sodium-Calcium Exchanger Antibody [NBP1-87808] - Lane 1: Marker [kDa] 206, 113, 82, 49, 32, 26, 18<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp<br/>Lane 4: Human cell line A-431

Anti-SLC8A3 antibody produced in rabbit - HPA001669 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SLC8A3: <B>Cat. No. HPA001669</B>: Immunohistochemical staining of human duodenum shows strong cytoplasmic positivity in enteroendocrine cells.

ANTI-SLC8A3(C-TERMINAL) antibody produced in rabbit - SAB1307026 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SLC8A3 (C-term): <B>Cat. No. SAB1307026</B>: SLC8A3 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35 μg/lane).

Anti-SLC8A3 antibody produced in rabbit - SAB2102225 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SLC8A3: <B>Cat. No.SAB2102225</B>: SLC8A3 in 721_B cell lysate with SLC8A3 antibody at 1.0 μg/mL.

SLC8A3 antibody - N-terminal region (ARP44074_P050) - ARP44074_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SLC8A3-Antibody-C-term - AP12808b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
SLC8A3 Antibody (C-term) (Cat. #AP12808b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SLC8A3 antibody detected the SLC8A3 protein (arrow).
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