DSE

Gene Symbol	DSE
Entrez Gene	29940
Alt Symbol	DSEP, DSEPI, EDSMC2, SART-2, SART2
Species	Human
Gene Type	protein-coding
Description	dermatan sulfate epimerase
Other Description	DS epimerase\|chondroitin-glucuronate 5-epimerase\|dermatan-sulfate epimerase\|squamous cell carcinoma antigen recognized by T-cells 2
Swissprots	Q9UL01 Q5R3K6
Accessions	EAW48229 EAW48230 Q9UL01 AF098066 AAF00087 AK095123 AK128607 BAG54699 AK293872 BAH11619 AK301513 BAH13501 AL832471 BC039245 AAH39245 BC043526 DB282412 DQ891261 ABM82187 DQ894447 ABM85373 XM_011535785 XP_011534087 NM_001080976 NP_001074445 NM_013352 NP_037484
Function	Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues. {ECO:0000269\|PubMed:16505484}.
Subcellular Location	Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity	Ubiquitously expressed with higher expression in kidney and ovary and lower expression in brain, colon and thymus. Also expressed in renal cell carcinomas, brain tumors, and in a part of melanomas and adenocarcinomas from organs other than the breast. Expressed in squamous cell carcinomas (SCC), glioma, and some adenocarcinoma cell lines, but not in breast cancer cell lines or any normal tissues (at protein level). {ECO:0000269\|PubMed:10679095}.
Top Pathways	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

SART2 (N-15) - sc-169252 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

SART2 (N-15): sc-169252. Western blot analysis of SART2 expression in human kidney tissue extract.

Anti-SART2 antibody - ab57131 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

Anti-SART2 antibody (ab57131) + immunogen

Anti-SART2 / DSE Antibody (aa505-818) - LS-C311595 from LifeSpan Bioscience

Prices	$250.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

SART2 Antibody - NBP1-87962 from Novus Biologicals

Prices	$129.00, $419.00
Sizes	25 µl, 100 µl
Host	Rabbit
Clonality	Polyclonal

SART2 Antibody - H00029940-B01 from Novus Biologicals

Prices	$349.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Western Blot: SART2 Antibody [H00029940-B01] - analysis of SART2 expression in transfected 293T cell line by SART2 MaxPab polyclonal antibody (B01). Lane1: SART2 transfected lysate (109.80 KDa). Lane2: Non-transfected lysate.

SART2 Antibody (6D4) - H00029940-M03 from Novus Biologicals

Prices	$359.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	6D4

Western Blot: SART2 Antibody (6D4) [H00029940-M03] - Analysis of DSE expression in transfected 293T cell line by DSE monoclonal antibody (M03), clone 6D4. Lane 1: DSE transfected lysate (Predicted MW: 109.8 KDa). Lane 2: Non-transfected lysate.

SART2 Antibody - H00029940-A01 from Novus Biologicals

Host	Mouse
Clonality	Polyclonal

Anti-DSE antibody produced in rabbit - HPA014764 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-DSE: <B>Cat. No. HPA014764</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human pancreas shows cytoplasmic positivity in exocrine glandular cells and islet cells.

Monoclonal Anti-SART2 antibody produced in mouse - WH0029940M3 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	6D4

<B>Immunoblotting</B><BR/>Monoclonal Anti-SART2, <B>Cat. No. WH0029940M3</B> used at the antibody concentration: 1 μg/mL. Specific band of ~37.11 kDa using immunogen protein lysate.

SART2-Antibody-monoclonal-M03 - AT3773a from Abgent, a WuXi AppTec company

Prices	$315.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	6D4

Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.74 KDa) .

SART2 antibody - 10452-1-AP from Acris Antibodies

Prices	$270.00
Sizes	150 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemical of paraffin-embedded human liver cancer using 10452-1-AP(DSE antibody) at dilution of 1:50 (under 10x lens)

SART2 antibody - 60041-1-Ig from Acris Antibodies

Prices	$270.00
Sizes	150 µl
Host	Mouse
Clonality	Monoclonal
Clone	2C9F7

COLO 320 cells were subjected to SDS PAGE followed by western blot with 60041-1-Ig(DSE antibody) at dilution of 1:300

SART2 antibody - H00029940-A01 from Acris Antibodies

Prices	$300.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

SART2 antibody - H00029940-B01 from Acris Antibodies

Prices	$360.00
Sizes	50 µl
Host	Mouse
Clonality	Polyclonal

Western Blot analysis of DSE expression in transfected 293T cell line (H00029940-T01) by DSE MaxPab polyclonal antibody.Lane1:SART2 transfect

SART2 antibody - H00029940-M03 from Acris Antibodies

Prices	$360.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	6D4

Detection limit for recombinant GST tagged SART2 is approximately 0.3ng/ml as a capture antibody.

DSE antibody - 10452-1-AP from Proteintech Group

Prices	$279.00
Sizes	con: 20 μg/150μl
Host	Rabbit
Clonality	Polyclonal

DSE antibody - 60041-1-Ig from Proteintech Group

Prices	$279.00
Sizes	con: 150 μg/150μl
Host	Mouse
Clonality	Monoclonal

DSE Antibody - EPP12455 from Elabscience

Prices	$296.00, $485.00
Sizes	120 μl, 200 μl
Host	Rabbit
Clonality	Polyclonal

Anti-DSE (full length) polyclonal antibody - DPABH-07648 from Creative Diagnostics

Host	Mouse
Clonality	Polyclonal

Monoclonal Antibody to Dermatan Sulfate Epimerase (DSE) - MAL449Hu21 from Uscn Life Science Inc.

Host	Mouse
Clonality	Monoclonal

Polyclonal Antibody to Dermatan Sulfate Epimerase (DSE) - PAL449Hu01 from Uscn Life Science Inc.

Host	Rabbit
Clonality	Polyclonal

DSE, Polyclonal Antibody - MBS2526862 from MyBioSource

Prices	$195.00, $270.00, $435.00
Sizes	60 µl, 120 µl, 200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-dermatan sulfate epimerase - 08A029940 from MP Biomedicals

Prices	$456.30
Sizes	100 μg
Host	Mouse
Clonality	Monoclonal
Clone	6D4

Monoclonal Antibody to Dermatan Sulfate Epimerase (DSE) - MAL449Hu21 from Cloud-clone

Host	Mouse
Clonality	Monoclonal

Polyclonal Antibody to Dermatan Sulfate Epimerase (DSE) - PAL449Hu01 from Cloud-clone

Host	Rabbit
Clonality	Polyclonal

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