DSE

Gene Symbol DSE
Entrez Gene 29940
Alt Symbol DSEP, DSEPI, EDSMC2, SART-2, SART2
Species Human
Gene Type protein-coding
Description dermatan sulfate epimerase
Other Description DS epimerase|chondroitin-glucuronate 5-epimerase|dermatan-sulfate epimerase|squamous cell carcinoma antigen recognized by T-cells 2
Swissprots Q9UL01 Q5R3K6
Accessions EAW48229 EAW48230 Q9UL01 AF098066 AAF00087 AK095123 AK128607 BAG54699 AK293872 BAH11619 AK301513 BAH13501 AL832471 BC039245 AAH39245 BC043526 DB282412 DQ891261 ABM82187 DQ894447 ABM85373 XM_011535785 XP_011534087 NM_001080976 NP_001074445 NM_013352 NP_037484
Function Converts D-glucuronic acid to L-iduronic acid (IdoUA) residues. {ECO:0000269|PubMed:16505484}.
Subcellular Location Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Ubiquitously expressed with higher expression in kidney and ovary and lower expression in brain, colon and thymus. Also expressed in renal cell carcinomas, brain tumors, and in a part of melanomas and adenocarcinomas from organs other than the breast. Expressed in squamous cell carcinomas (SCC), glioma, and some adenocarcinoma cell lines, but not in breast cancer cell lines or any normal tissues (at protein level). {ECO:0000269|PubMed:10679095}.
Top Pathways Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

Human SART2 full length protein - ab162275 from Abcam

Category Protein
Source Wheat germ
Species Human
ab162275 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human SART2 protein fragment - ab162276 from Abcam

Category Protein
Source Wheat germ
Species Human
ab162276 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Recombinant Human SART2 Protein - H00029940-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Recombinant Human SART2 Protein - H00029940-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

DSE-Antibody-Center-Blocking-Peptide - BP9001c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

SART2 - H00029940-P01 from Acris Antibodies

Category Protein
Prices $310.00
Sizes 2 µg
Species Human

SART2 - H00029940-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

SART2 - H00029940-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

DSE fusion protein - ag0695 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

DSE fusion protein - ag16696 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Dermatan Sulfate Epimerase (DSE) - RPL449Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Dermatan Sulfate Epimerase (DSE) - RPL449Hu01 from Cloud-clone

Category Protein
Source E.coli
Species Human

SART2 Recombinant Protein Antigen - NBP1-87962PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

DSE Peptide, Human - M34GP04563H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

SART2 Recombinant Protein Antigen - NBP2-58454PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human
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