Gene Symbol | RND1 |
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Entrez Gene | 27289 |
Alt Symbol | ARHS, RHO6, RHOS |
Species | Human |
Gene Type | protein-coding |
Description | Rho family GTPase 1 |
Other Description | ras homolog gene family, member S|rho-related GTP-binding protein Rho6 |
Swissprots | Q92730 A8K9P7 |
Accessions | EAW58019 Q92730 AB040147 BAB17851 AF498967 AAM21114 AK124288 AK292762 BAF85451 AL359573 BC026356 AAH26356 N79562 Y07923 CAA69228 NM_014470 NP_055285 |
Function | Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments. {ECO:0000269|PubMed:11095956}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:11940653}; Lipid-anchor {ECO:0000269|PubMed:11940653}; Cytoplasmic side {ECO:0000269|PubMed:11940653}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:11940653}. |
Tissue Specificity | Mostly expressed in brain and liver. |
Top Pathways | Axon guidance |
Rnd1 (H-98) - sc-368619 from Santa Cruz Biotechnology
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Rnd1 (K-16) - sc-25029 from Santa Cruz Biotechnology
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Anti-RND1 antibody - ab81143 from Abcam
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Anti-RND1 antibody - ab69419 from Abcam
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Anti-RND1 antibody [1C3] - ab118993 from Abcam
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Anti-RND1 antibody - C-terminal - ab79918 from Abcam
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Anti-RND1 Antibody - LS-C94775 from LifeSpan Bioscience
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Anti-RND1 Antibody (C-Terminus) - LS-C145655 from LifeSpan Bioscience
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RND1 Antibody (1C3) - NBP2-03000 from Novus Biologicals
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RND1 Antibody - H00027289-A01 from Novus Biologicals
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RND1 Antibody - NBP1-20193 from Novus Biologicals
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RND1 Antibody - H00027289-B01P from Novus Biologicals
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Anti-RND1 antibody produced in mouse - SAB1407353 from Sigma-Aldrich
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Monoclonal Anti-RND1 antibody produced in mouse - SAB4100061 from Sigma-Aldrich
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Monoclonal Anti-RND1 antibody produced in mouse - SAB4100060 from Sigma-Aldrich
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RND1 antibody - C-terminal region (ARP61632_P050) - ARP61632_P050 from Aviva Systems Biology
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RND1 / RHO6 antibody - H00027289-A01 from Acris Antibodies
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RND1 / RHO6 antibody - H00027289-B01P from Acris Antibodies
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RND1 antibody - 13786-1-AP from Proteintech Group
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RND1 Antibody - GWB-MW331G from Genway Biotech
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Anti-RND1 (aa 183-232) polyclonal antibody - DPABH-08152 from Creative Diagnostics
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Anti-RND1 monoclonal antibody - DCABH-13269 from Creative Diagnostics
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Anti-RND1 monoclonal antibody, clone 2D4 - DCABH-838 from Creative Diagnostics
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RND1 antibody [1C3] - GTX83708 from GeneTex
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RND1 antibody [4F12] - GTX83709 from GeneTex
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