Gene Symbol | AQP3 |
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Entrez Gene | 360 |
Alt Symbol | AQP-3, GIL |
Species | Human |
Gene Type | protein-coding |
Description | aquaporin 3 (Gill blood group) |
Other Description | aquaglyceroporin-3|aquaporin 3 (GIL blood group)|aquaporin-3 |
Swissprots | B2RE16 Q92482 Q6FGW6 Q6FGT2 O00108 D3DRL3 A8K843 |
Accessions | AAY68214 BAA09077 CCF76945 EAW58500 EAW58501 EAW58502 EAW58503 EAW58504 Q92482 AB001325 BAA19237 AJ493597 CAD38526 AK095363 AK292208 BAF84897 AK303206 BAG64296 AK315760 BAG38113 BC012988 BC013566 AAH13566 BF437236 BT007199 AAP35863 CR541991 CAG46788 CR542025 CAG46822 DA976040 XM_011517864 XP_011516166 NM_004925 NP_004916 |
Function | Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism (By similarity). {ECO:0000250}. |
Subcellular Location | Basolateral cell membrane; Multi-pass membrane protein. Note=In collecting ducts of kidney. |
Tissue Specificity | Widely expressed in epithelial cells of kidney (collecting ducts) and airways, in keratinocytes, immature dendritic cells and erythrocytes. Isoform 2 is not detectable in erythrocytes at the protein level. |
Top Pathways | Vasopressin-regulated water reabsorption |
AQP3 (H-80) - sc-20811 from Santa Cruz Biotechnology
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AQP3 (C-18) - sc-9885 from Santa Cruz Biotechnology
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Anti-Aquaporin 3 antibody - ab125219 from Abcam
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Anti-Aquaporin 3 antibody - ab15117 from Abcam
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Anti-AQP3 / Aquaporin 3 Antibody (C-Terminus) - LS-C3802 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (C-Terminus) - LS-C3804 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (aa165-214) - LS-C199770 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (aa268-292, Atto 390) - LS-C229800 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (aa268-292, Atto 488) - LS-C229801 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (aa268-292, Atto 565) - LS-C229802 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (aa268-292, Atto 594) - LS-C229803 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (aa268-292, Atto 633) - LS-C229804 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (Val214) - LS-C177712 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (aa268-292, Atto 655) - LS-C229805 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (aa268-292, Atto 680) - LS-C229806 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (aa268-292, Atto 700) - LS-C229807 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (aa268-292, AP) - LS-C229808 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (aa268-292, APC) - LS-C229809 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (aa268-292) IHC-plus⢠- LS-B8185 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (aa268-292, Biotin) - LS-C229810 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (aa268-292, FITC) - LS-C229811 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (aa268-292, PerCP) - LS-C229813 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (aa268-292, PE, Atto 594) - LS-C229814 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (aa268-292, RPE) - LS-C229815 from LifeSpan Bioscience
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Anti-AQP3 / Aquaporin 3 Antibody (aa268-292, SA) - LS-C229816 from LifeSpan Bioscience
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