AQP3

Gene Symbol	AQP3
Entrez Gene	360
Alt Symbol	AQP-3, GIL
Species	Human
Gene Type	protein-coding
Description	aquaporin 3 (Gill blood group)
Other Description	aquaglyceroporin-3|aquaporin 3 (GIL blood group)|aquaporin-3
Swissprots	B2RE16 Q92482 Q6FGW6 Q6FGT2 O00108 D3DRL3 A8K843
Accessions	AAY68214 BAA09077 CCF76945 EAW58500 EAW58501 EAW58502 EAW58503 EAW58504 Q92482 AB001325 BAA19237 AJ493597 CAD38526 AK095363 AK292208 BAF84897 AK303206 BAG64296 AK315760 BAG38113 BC012988 BC013566 AAH13566 BF437236 BT007199 AAP35863 CR541991 CAG46788 CR542025 CAG46822 DA976040 XM_011517864 XP_011516166 NM_004925 NP_004916
Function	Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism (By similarity). {ECO:0000250}.
Subcellular Location	Basolateral cell membrane; Multi-pass membrane protein. Note=In collecting ducts of kidney.
Tissue Specificity	Widely expressed in epithelial cells of kidney (collecting ducts) and airways, in keratinocytes, immature dendritic cells and erythrocytes. Isoform 2 is not detectable in erythrocytes at the protein level.
Top Pathways	Vasopressin-regulated water reabsorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Aquaporin 3 peptide - ab80550 from Abcam Category Peptide Prices $285.00 Sizes 50 µg

Aquaporin 3 peptide - ab195690 from Abcam Category Peptide Prices $181.00 Sizes 1 ml

AQP3 / Aquaporin 3 Antibody Blocking Peptide - LS-E6521 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AQP3-Antibody-Center-Blocking-Peptide - BP19289c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Aquaporin-3 / AQP3 control peptide - AP09889CP-N from Acris Antibodies Category Peptide Prices $235.00 Sizes 250 µg

Recombinant Human AQP3 - AQP3-465H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Aquaporin 3, Gill Blood Group (AQP3) - RPA581Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Aquaporin 3 Blocking Peptide - CBP3133 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Bovine, Monkey, Pig, Sheep, Zebrafish

AQP3 (V214) Peptide - BS3671P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

AQP3 Peptide - abx164774 from Abbexa Category Peptide Species Human, Mouse, Rat

Aquaporin-3 / AQP3 - TP301856 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Aquaporin-3 Recombinant Protein Antigen - NBP2-33872PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

AQP3 Peptide, Human - M34GP00812H from Creative Peptides Category Peptide Source Synthetic. Species Human

AQP3 fusion protein - Ag23132 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

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