Gene Symbol | JSRP1 |
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Entrez Gene | 126306 |
Alt Symbol | JP-45, JP45 |
Species | Human |
Gene Type | protein-coding |
Description | junctional sarcoplasmic reticulum protein 1 |
Other Description | 2310032K21Rik|homolog of mouse skeletal muscle sarcoplasmic reticulum protein JP-45|junctional-face membrane protein of 45 kDa homolog|skeletal muscle sarcoplasmic reticulum protein JP-45 |
Swissprots | Q96MG2 |
Accessions | EAW69396 Q96MG2 AK056978 BAB71330 AW137573 BC021201 AAH21201 DA897543 DA898560 EU831408 ACE87095 EU831501 ACE86420 NM_144616 NP_653217 |
Function | Involved in skeletal muscle excitation/contraction coupling (EC), probably acting as a regulator of the voltage- sensitive calcium channel CACNA1S. EC is a physiological process whereby an electrical signal (depolarization of the plasma membrane) is converted into a chemical signal, a calcium gradient, by the opening of ryanodine receptor calcium release channels. May regulate CACNA1S membrane targeting and activity. {ECO:0000269|PubMed:22927026}. |
Subcellular Location | Sarcoplasmic reticulum membrane {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}. Note=Colocalizes with ryanodine receptors at the sarcoplasmic reticulum triad membranes. {ECO:0000250}. |
JP-45 (G-14) - sc-139145 from Santa Cruz Biotechnology
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JSRP1 Antibody - NBP1-81998 from Novus Biologicals
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JSRP1 Antibody (6A9) - H00126306-M02-100ug from Novus Biologicals
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Monoclonal Anti-JSRP1 antibody produced in mouse - SAB1412915 from Sigma-Aldrich
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Anti -JSRP1 (Junctional Sarcoplasmic Reticulum Protein 1, JP45, JP-45) - 211582 from USBiological Life Science
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JSRP1 Polyclonal Antibody - A5134 from ABclonal
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JSRP1 antibody - 70R-18048 from Fitzgerald
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JSRP1 Antibody - abx003930 from Abbexa
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JSRP1 antibody - 10854-1-AP from Acris Antibodies
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JSRP1 antibody - H00126306-B01P from Acris Antibodies
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JSRP1 antibody - H00126306-M02 from Acris Antibodies
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Anti-JSRP1, Polyclonal Antibody - 25-A5134 from ARP American Research Products
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JSRP1 antibody - STJ27116 from St John's Laboratory Ltd
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JP45/JSRP1 antibody - 10854-1-AP from Proteintech Group
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JSRP1 - MBS9126812 from MyBioSource
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junctional sarcoplasmic reticulum protein 1 , Polyclonal Antibody - MBS716306 from MyBioSource
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JSRP1 - A5134 from NeoScientific
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JP45; JSRP1 Antibody - EPP14525 from Elabscience
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Anti-JSRP1 polyclonal antibody - DPAB-DC511 from Creative Diagnostics
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JSRP1 Antibody - SH-A13046 from Novatein Biosciences
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Anti-JSRP1 antibody produced in rabbit - HPA044741 from Sigma-Aldrich
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anti-JP45/JSRP1 antibody - A004450 from Biobool
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JP45/JSRP1, Polyclonal Antibody - MBS7600683 from MyBioSource
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JP45 antibody - orb395217 from Biorbyt
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