CYP26A1

Gene Symbol CYP26A1
Entrez Gene 1592
Alt Symbol CP26, CYP26, P450RAI, P450RAI1
Species Human
Gene Type protein-coding
Description cytochrome P450, family 26, subfamily A, polypeptide 1
Other Description P450, retinoic acid-inactivating, 1|cytochrome P450 26A1|cytochrome P450 retinoic acid-inactivating 1|cytochrome P450, subfamily XXVIA, polypeptide 1|cytochrome P450RAI|hP450RAI|retinoic acid 4-hydroxylase|retinoic acid-metabolizing cytochrome
Swissprots Q5VXH9 O43174 Q5VXI0 B3KNI4
Accessions EAW50078 EAW50079 O43174 AF005418 AAB88881 AK027560 BAG51346 AK075374 BC156283 AAI56284 BC157063 AAI57064 NM_000783 NP_000774 NM_057157 NP_476498
Function Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18- hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA.
Subcellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Tissue Specificity Highest levels in adult liver, heart, pituitary gland, adrenal gland, placenta and regions of the brain. {ECO:0000269|PubMed:9826557}.
Top Pathways Retinol metabolism

CYP26 (G-14) - sc-74386 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYP26 (G-14): sc-74386. Western blot analysis of CYP26 expression in mouse liver tissue extract.

CYP26A1 (F27 P6 A1) - sc-53618 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP26A1 (F27 P6 A1): sc-53618. Western blot analysis of CYP26A1 expression in human ovary tumor tissue extract.

Anti-CYP26A1 antibody - ab171876 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-CYP26A1 antibody (ab171876) at 1 µg/mlLane 1 : CYP26A1 transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgGb at 1/2500 dilution

Anti-CYP26A1 antibody - ab135521 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CYP26A1 antibody (ab135521) at 1/60 dilution + Jurkat cell line lysate at 35 µg

Anti-CYP26A1 antibody - ab107527 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
ab107527, at a concentration of 3.8 µg/ml, staining CYP26A1 in apparent adhesion sites between axons of paraffin embedded Human cerebellum by Immunohistochemistry. Steamed antigen retrieval with citrate buffer pH 6 and AP-staining were used.

Anti-CYP26A1 antibody [EPR11841] - ab172474 from Abcam

Prices $387.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11841
Immunohistochemical analysis of paraffin embedded Human liver tissue labeling CYP26A1 with ab172474 at 1/250 dilution.

Anti-CYP26A1 antibody [F27 P6 A1] - ab118446 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone F27 P6 A1
ab118446, at 10 µg/ml, staining CYP26A1 in Formalin-fixed, Paraffin-embedded Human Placenta tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Anti-CYP26 / CYP26A1 Antibody (C-Terminus) - LS-C36126 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP26 / CYP26A1 Antibody - LS-C36125 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP26 / CYP26A1 Antibody (His277) - LS-C191999 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP26 / CYP26A1 Antibody (Internal) - LS-C210066 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP26 / CYP26A1 Antibody (N-Terminus) - LS-C210067 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP26 / CYP26A1 Antibody (aa250-495, Biotin) - LS-C299538 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP26 / CYP26A1 Antibody (aa250-495, FITC) - LS-C303893 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP26 / CYP26A1 Antibody - LS-C307837 from LifeSpan Bioscience

Host Mouse
Clonality Polyclonal

Anti-CYP26 / CYP26A1 Antibody (aa251-300) - LS-C119490 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of extracts from HepG2/HeLa/293 cells, using Cytochrome P450 26A1 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-CYP26 / CYP26A1 Antibody (aa250-495) - LS-C294104 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of recombinant CYP26 / CYP26A1.

Anti-CYP26 / CYP26A1 Antibody (Internal) - LS-C98635 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of anti-CYP26A1 Antibody in Jurkat cell line lysates (35 ug/lane). CYP26A1(arrow) was detected using the purified antibody.

Anti-CYP26 / CYP26A1 Antibody (N-Terminus) - LS-C345112 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of CYP26A1 Antibody with human Fetal Liver lysate.

Anti-CYP26 / CYP26A1 Antibody (aa476-506) - LS-C167213 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CYP26A1 Antibody IHC of formalin-fixed and paraffin-embedded brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-CYP26 / CYP26A1 Antibody (C-Terminus) IHC-plus™ - LS-B2916 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
A. IHC of liposarcoma cells using CYP26A1 antibody (LS-B2916). B. Western blot on recombinant protein corresponding to C-terminal region of CYP26A1 protein using CYP26A1 antibody.

Anti-CYP26 / CYP26A1 Antibody (Internal) IHC-plus™ - LS-B4140 from LifeSpan Bioscience

Host Goat
Clonality Polyclonal
Anti-CYP26A1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4140 concentration 3.75 ug/ml.

CYP26A1 Antibody - NBP2-16061 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CYP26A1 Antibody [NBP2-16061] - Mouse tissue extract (50 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with CYP26A1 antibody diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.

CYP26A1 Antibody - NBP1-52388 from Novus Biologicals

Prices $329.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Immunohistochemistry-Paraffin: CYP26A1 Antibody [NBP1-52388] - Analysis of anti-CYP26A1 antibody with human brain, cerebellum, white matter at concentration 3.75 ug/ml.

CYP26A1 Antibody - NBP1-55814 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: CYP26A1 Antibody [NBP1-55814] - Analysis of extracts from HepG2/HeLa/293 cells, using CYP26A1 Antibody. The lane on the right is treated with the synthesized peptide.
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