PLEC

Gene Symbol	PLEC
Entrez Gene	5339
Alt Symbol	EBS1, EBSO, HD1, LGMD2Q, PCN, PLEC1, PLEC1b, PLTN
Species	Human
Gene Type	protein-coding
Description	plectin
Other Description	hemidesmosomal protein 1|plectin 1, intermediate filament binding protein 500kDa
Swissprots	Q6S381 Q15149 Q6S377 Q6S376 Q6S380 Q15148 Q6S382 Q6S383 Q16640 Q6S378 Q6S379
Accessions	AAB05428 CAA91196 CAP07515 CAP11483 CAR97097 CAT82346 EAW82170 EAW82171 EAW82172 EAW82173 EAW82174 Q15149 AF330791 AAL37482 AF330792 AAL37483 AY480044 AAR95677 AY480045 AAR95678 AY480046 AAR95679 AY480047 AAR95680 AY480048 AAR95681 AY480049 AAR95682 AY480050 AAR95683 AY480051 AAR95684 BC007597 AAH07597 BC013206 BM681271 BP231761 BP312608 BP315878 BP321327 BP359323 U53204 AAB05427 X97053 CAA65765 Z36817 XM_005250976 XP_005251033 XM_005250978 XP_005251035 XM_005250979 XP_005251036 XM_005250980 XP_005251037 XM_005250981 XP_005251038 XM_005250982 XP_005251039 XM_005250983 XP_005251040 XM_005250984 XP_005251041 XM_006716588 XP_006716651 XM_006716589 XP_006716652 XM_006716590 XP_006716653 XM_011517130 XP_011515432 XM_011517131 XP_011515433 XM_011517132 XP_011515434 NM_000445 NP_000436 NM_201378 NP_958780 NM_201379 NP_958781 NM_201380 NP_958782 NM_201381 NP_958783 NM_201382 NP_958784 NM_201383 NP_958785 NM_201384 NP_958786
Function	Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofibers integrity. {ECO:0000269|PubMed:12482924, ECO:0000269|PubMed:21109228}.
Subcellular Location	Cytoplasm, cytoskeleton {ECO:0000269|PubMed:12482924}. Cell junction, hemidesmosome {ECO:0000269|PubMed:12482924}.
Tissue Specificity	Widely expressed with highest levels in muscle, heart, placenta and spinal cord.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Recombinant Human Plectin Protein - H00005339-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Plectin - H00005339-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Plectin - H00005339-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Recombinant Human PLEC, His-tagged - PLEC-30873TH from Creative Biomart Category Protein Source E. coli

Recombinant Plectin (PLEC) - RPC754Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Human Plectin(PLEC) ,partial - CSB-YP619965HU CSB-EP619965HU CSB-BP619965HU CSB-MP619965HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Plectin Protein (Recombinant) - abx167116 from Abbexa Category Protein Source Human Species Human

Plectin, Recombinant Protein - MBS2031199 from MyBioSource Category Protein Prices $190.00, $410.00, $635.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

Plectin (PLEC), partial, Recombinant Protein - MBS1373719 from MyBioSource Category Protein Prices $835.00, $835.00, $1,055.00, $1,055.00, $1,170.00, $1,170.00, $1,620.00, $1,620.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Plectin Recombinant Protein Antigen - NBP1-84020PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Plectin Recombinant Protein Antigen - NBP1-84019PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PLEC Peptide, Human - M34GP11918H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Plectin (PLEC) - RPU53846 from Biomatik Category Protein Prices $202.00, $394.00, $630.00, $751.12 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

PLEC Recombinant Protein (OPCD06265) - OPCD06265 from Aviva Systems Biology Category Protein Source E.coli Species Human

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