Gene Symbol | ITPR2 |
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Entrez Gene | 3709 |
Alt Symbol | ANHD, CFAP48, IP3R2 |
Species | Human |
Gene Type | protein-coding |
Description | inositol 1,4,5-trisphosphate receptor, type 2 |
Other Description | IP3 receptor|IP3R 2|cilia and flagella associated protein 48|inositol 1,4,5-triphosphate receptor, type 2|inositol 1,4,5-trisphosphate receptor type 2|insP3R2|type 2 InsP3 receptor|type 2 inositol 1,4,5-trisphosphate receptor |
Swissprots | Q14571 O94773 |
Accessions | AFI41831 EAW96534 EAW96535 Q14571 AB012610 BAA33961 AI339141 AK307686 AK307712 AK310504 AL711179 AY429550 BC172383 AAI72383 BE439696 BP314401 BP364657 BU173910 BX495410 CA419735 D26350 BAA05384 DB144849 XM_011520645 XP_011518947 XM_011520646 XP_011518948 XR_931288 NM_002223 NP_002214 |
Function | Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA (By similarity). {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
Tissue Specificity | Isoform Short is found in skeletal muscle and heart. |
Top Pathways | Inflammatory mediator regulation of TRP channels, Oxytocin signaling pathway, cGMP-PKG signaling pathway, Thyroid hormone synthesis, Estrogen signaling pathway |
IP3R-II (A-5) - sc-398434 from Santa Cruz Biotechnology
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IP3R-II (C-20) - sc-7278 from Santa Cruz Biotechnology
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IP3R-II (E-15) - sc-26384 from Santa Cruz Biotechnology
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IP3R-II (L-19) - sc-26385 from Santa Cruz Biotechnology
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IP3R-II (P-20) - sc-26386 from Santa Cruz Biotechnology
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IP3R-I/II/III (B-2) - sc-377518 from Santa Cruz Biotechnology
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IP3R-I/II/III (H-300) - sc-28613 from Santa Cruz Biotechnology
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Anti-ITPR2 antibody - ab55981 from Abcam
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Anti-ITPR2 / IP3 Receptor Type 2 Antibody (C-Terminus) - LS-C24911 from LifeSpan Bioscience
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Anti-ITPR2 / IP3 Receptor Type 2 Antibody (C-Terminus) - LS-C46910 from LifeSpan Bioscience
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Anti-ITPR2 / IP3 Receptor Type 2 Antibody (C-Terminus) - LS-C145150 from LifeSpan Bioscience
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Anti-ITPR2 / IP3 Receptor Type 2 Antibody (aa53-102) - LS-C205664 from LifeSpan Bioscience
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Anti-ITPR2 / IP3 Receptor Type 2 Antibody (C-Terminus) IHC-plus⢠- LS-B9648 from LifeSpan Bioscience
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Anti-ITPR2 / IP3 Receptor Type 2 Antibody (aa1152-1164) IHC-plus⢠- LS-B3238 from LifeSpan Bioscience
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ITPR2 Antibody - NB100-2466 from Novus Biologicals
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ITPR2 Antibody - NBP1-49587 from Novus Biologicals
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Rabbit Anti-ITPR2 Polyclonal Antibody - bs-4243R from Bioss
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Anti-ITPR2 antibody produced in rabbit - SAB4301087 from Sigma-Aldrich
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ITPR2 Antibody - N-terminal region (ARP35068_P050) - ARP35068_P050 from Aviva Systems Biology
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ITPR2-Antibody-internal-region - AF2483a from Abgent, a WuXi AppTec company
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IP3 Receptor II antibody - GTX82888 from GeneTex
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ITPR2 antibody, Internal - GTX89438 from GeneTex
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ITPR2 Antibody (OAEB00085) - OAEB00085 from Aviva Systems Biology
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Anti -ITPR2 (Inositol 1,4,5-trisphosphate Receptor Type 2, IP3 Receptor Isoform 2, IP3R 2,InsP3R2, Type 2 Inositol 1,4,5-trisphosphate Receptor, Type 2 InsP3 Receptor) - I8472-03A from USBiological Life Science
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Anti -ITPR2 (Inositol 1,4,5-trisphosphate Receptor Type 2, IP3 Receptor Isoform 2, IP3R 2,InsP3R2, Type 2 Inositol 1,4,5-trisphosphate Receptor, Type 2 InsP3 Receptor) - I8472-03B from USBiological Life Science
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