ITPR2

Gene Symbol	ITPR2
Entrez Gene	3709
Alt Symbol	ANHD, CFAP48, IP3R2
Species	Human
Gene Type	protein-coding
Description	inositol 1,4,5-trisphosphate receptor, type 2
Other Description	IP3 receptor|IP3R 2|cilia and flagella associated protein 48|inositol 1,4,5-triphosphate receptor, type 2|inositol 1,4,5-trisphosphate receptor type 2|insP3R2|type 2 InsP3 receptor|type 2 inositol 1,4,5-trisphosphate receptor
Swissprots	Q14571 O94773
Accessions	AFI41831 EAW96534 EAW96535 Q14571 AB012610 BAA33961 AI339141 AK307686 AK307712 AK310504 AL711179 AY429550 BC172383 AAI72383 BE439696 BP314401 BP364657 BU173910 BX495410 CA419735 D26350 BAA05384 DB144849 XM_011520645 XP_011518947 XM_011520646 XP_011518948 XR_931288 NM_002223 NP_002214
Function	Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA (By similarity). {ECO:0000250}.
Subcellular Location	Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity	Isoform Short is found in skeletal muscle and heart.
Top Pathways	Inflammatory mediator regulation of TRP channels, Oxytocin signaling pathway, cGMP-PKG signaling pathway, Thyroid hormone synthesis, Estrogen signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IP3R-II CRISPR/Cas9 KO Plasmid (h) - sc-401067 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IP3R-II HDR Plasmid (h) - sc-401067-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IP3R-II Double Nickase Plasmid (h) - sc-401067-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IP3R-II Double Nickase Plasmid (h2) - sc-401067-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IP3R-II CRISPR Activation Plasmid (h) - sc-401067-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IP3R-II CRISPR Activation Plasmid (h2) - sc-401067-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

IP3R-II Lentiviral Activation Particles (h) - sc-401067-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IP3R-II Lentiviral Activation Particles (h2) - sc-401067-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IP3R-II siRNA (h) - sc-35698 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

IP3R-II shRNA Plasmid (h) - sc-35698-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

IP3R-II shRNA (h) Lentiviral Particles - sc-35698-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ITPR2 RNAi - H00003709-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU118761 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® esiRNA - EHU056071 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN10839 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10839 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

ITPR2 siRNA (Human) - CRH2497 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ITPR2, siRNA - MBS8225733 from MyBioSource Category siRNA Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

IP3R-II HDR Plasmid (h2) - sc-401067-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

IP3R-II CRISPR/Cas9 KO Plasmid (h2) - sc-401067-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human ITPR2 (NM_002223.2) - SHH321685 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human ITPR2(NM_002223.2) - SHL184908 from Creative biogene Category siRNA Species Reactivities Human

ITPR2 shRNA Plasmid (Human) - CHH2497 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

ITPR2 miRNA 3'UTR clone - MiUTR4H-TG04620 from Creative biogene Species Reactivities Human

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