P2RY12

Gene Symbol	P2RY12
Entrez Gene	64805
Alt Symbol	ADPG-R, BDPLT8, HORK3, P2T(AC), P2Y(12)R, P2Y(AC), P2Y(ADP), P2Y(cyc), P2Y12, SP1999
Species	Human
Gene Type	protein-coding
Description	purinergic receptor P2Y, G-protein coupled, 12
Other Description	ADP-glucose receptor|G-protein coupled receptor SP1999|Gi-coupled ADP receptor HORK3|P2Y purinoceptor 12|P2Y12 platelet ADP receptor|purinergic receptor P2RY12|putative G-protein coupled receptor
Swissprots	D3DNJ5 Q546J7 Q9H244
Accessions	AAL32292 BAB89309 EAW78803 EAW78804 Q9H244 AA810452 AB052684 BAB60824 AF313449 AAG48944 AF321815 AAK00948 AJ320495 CAC87144 AK292096 BAF84785 AK303714 BAG64695 AK316575 BAG38164 AW015793 AW976204 AY136754 AAN01280 BC017898 AAH17898 BM926255 DA179496 DA267276 DA343254 DB306976 DC313627 DQ893186 ABM84112 DQ896506 ABM87505 NM_022788 NP_073625 NM_176876 NP_795345
Function	Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation. {ECO:0000269|PubMed:11104774, ECO:0000269|PubMed:11196645, ECO:0000269|PubMed:11502873, ECO:0000269|PubMed:12578987, ECO:0000269|PubMed:24670650, ECO:0000269|PubMed:24784220}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:11196645, ECO:0000269|PubMed:12578987, ECO:0000269|PubMed:24670650, ECO:0000269|PubMed:24784220}; Multi-pass membrane protein {ECO:0000269|PubMed:11196645, ECO:0000269|PubMed:12578987, ECO:0000269|PubMed:24670650, ECO:0000269|PubMed:24784220}.
Tissue Specificity	Highly expressed in the platelets, lower levels in the brain. Lowest levels in the lung, appendix, pituitary and adrenal gland. Expressed in the spinal cord and in the fetal brain. {ECO:0000269|PubMed:11104774, ECO:0000269|PubMed:11196645, ECO:0000269|PubMed:11502873}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

P2RY12 / P2Y12 Antibody Blocking Peptide - LS-E28807 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

P2RY12 / P2Y12 Antibody Blocking Peptide - LS-E28808 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

P2RY12 / P2Y12 Blocking Peptide - LS-E28317 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

P2RY12 Blocking Peptide - 33R-9419 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

P2RY12 fusion protein - Ag2601 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, T-GST Species Human

Recombinant Human P2RY12, GST-tagged - P2RY12-1497H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Purinergic Receptor P2Y, G Protein Coupled 12 (P2RY12) - RPG086Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Purinergic Receptor P2Y, G Protein Coupled 12 (P2RY12) - RPG086Hu01 from Cloud-clone Category Protein Source E.coli Species Human

P2RY12 / P2Y12 Blocking Peptide - LS-E39735 from LifeSpan Bioscience Category Peptide Prices $100.00 Sizes 50 µg

P2RY12 / P2Y12 (transcript variant 1) - TP305005 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

P2Y12/P2RY12 Recombinant Protein Antigen - NBP2-33870PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

P2Y12/P2RY12 Recombinant Protein Antigen - NBP1-89673PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

P2RY12 Peptide, Human - M34GP11207H from Creative Peptides Category Peptide Source Synthetic. Species Human

P2Y purinoceptor 12 (P2RY12), Recombinant Protein - MBS7025273 from MyBioSource Category Protein Prices $1,150.00, $2,135.00, $3,345.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

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