PERP

Gene Symbol PERP
Entrez Gene 64065
Alt Symbol KCP1, KRTCAP1, PIGPC1, THW, dJ496H19.1
Species Human
Gene Type protein-coding
Description PERP, TP53 apoptosis effector
Other Description 1110017A08Rik|KCP-1|keratinocyte associated protein 1|keratinocyte-associated protein 1|keratinocytes associated protein 1|p53 apoptosis effector related to PMP-22|p53 apoptosis effector related to PMP22|p53-induced protein PIGPC1|transmembrane protein THW
Swissprots Q9H230 Q8NC16 Q8N1J6 Q9H1C5 Q8IWS3 B2RB73 E1P590 Q96FX8
Accessions CAF85829 CCF76964 EAW47920 EAW47921 Q96FX8 AF317550 AAG35063 AJ251830 CAC17766 AK074585 BAC11074 AK075082 BAC11390 AK093516 BAG52734 AK097387 BAG53462 AK097958 BAC05205 AK225907 AK314526 BAG37120 AY157578 AAO13162 BC010163 AAH10163 BU674771 CA310443 CX784592 DA750046 DQ892670 ABM83596 DR422553 EU176724 ABW03525 NM_022121 NP_071404
Function Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity). {ECO:0000250}.
Subcellular Location Cell junction, desmosome. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Associated with desmosomes. {ECO:0000250}.
Tissue Specificity Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts. {ECO:0000269|PubMed:12752121}.
Top Pathways p53 signaling pathway

Perp (FL-193) - sc-67184 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Perp (FL-193): sc-67184. Immunoperoxidase staining of formalin fixed, paraffin-embedded human skin tissue showing cytoplasmic staining of keratinocytes, Langerhans and melanocytes.

Perp (N-15) - sc-48262 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Perp (N-15): sc-48262. Western blot analysis of Perp expression in non-transfected: sc-117752 (A) and human Perp transfected: sc-159609 (B) 293T whole cell lysates.

Anti-PERP antibody - ab5986 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of PERP expression in A431 whole cell lysates in the absence (A) and presence (B) of blocking peptide with anti- PERP at 1 µg /ml.

Anti-PERP antibody - ab94337 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PERP antibody [EPR7885] - ab129083 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7885
All lanes : Anti-PERP antibody [EPR7885] (ab129083) at 1/1000 dilutionLane 1 : Mouse heart lysateLane 2 : Rat heart lysateLane 3 : A431 lysateLane 4 : HACAT lysateLane 5 : Human skin lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-PERP Antibody (aa162-191, Azide-free, HRP) - LS-C248451 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PERP Antibody (aa162-191, APC) - LS-C250007 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PERP Antibody (aa127-193) - LS-C311684 from LifeSpan Bioscience

Prices $250.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PERP Antibody (aa161-191) - LS-C323938 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PERP Antibody (aa107-156) - LS-C107965 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PERP antibody LS-C107965 Western blot of PANC1 cell lysate.

Anti-PERP Antibody (C-Terminus, clone EPR7885) - LS-C152511 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7885
Immunofluorescent staining of A431 cells using anti-PERP antibody.

Anti-PERP Antibody (aa162-191) - LS-C163522 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PERP Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human heart tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-PERP Antibody (aa172-185) IHC-plus™ - LS-B11149 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-PERP antibody IHC staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11149 concentration 5 ug/ml.

Anti-PERP Antibody (C-Terminus) IHC-plus™ - LS-B1389 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PERP antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1389 concentration 5 ug/ml.

Anti-PERP Antibody (aa37-50) - LS-C40701 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PERP Antibody (aa37-50) - LS-C49331 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PERP Antibody (aa175-193) - LS-C83546 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PERP Antibody (aa37-50) - LS-C87099 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PERP Antibody (C-Terminus) - LS-C121280 from LifeSpan Bioscience

Prices $530.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PERP Antibody (aa162-191, AP) - LS-C238922 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PERP Antibody (aa162-191, Biotin) - LS-C238923 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PERP Antibody (aa162-191, FITC) - LS-C238924 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PERP Antibody (aa162-191, PE) - LS-C238926 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

PERP Antibody - NBP1-85173 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: PERP Antibody [NBP1-85173] - Staining of human skin shows moderate positivity in stratum corneum.

PERP Antibody - NB500-231 from Novus Biologicals

Prices $229.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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