PERP

Gene Symbol PERP
Entrez Gene 64065
Alt Symbol KCP1, KRTCAP1, PIGPC1, THW, dJ496H19.1
Species Human
Gene Type protein-coding
Description PERP, TP53 apoptosis effector
Other Description 1110017A08Rik|KCP-1|keratinocyte associated protein 1|keratinocyte-associated protein 1|keratinocytes associated protein 1|p53 apoptosis effector related to PMP-22|p53 apoptosis effector related to PMP22|p53-induced protein PIGPC1|transmembrane protein THW
Swissprots Q9H230 Q8NC16 Q8N1J6 Q9H1C5 Q8IWS3 B2RB73 E1P590 Q96FX8
Accessions CAF85829 CCF76964 EAW47920 EAW47921 Q96FX8 AF317550 AAG35063 AJ251830 CAC17766 AK074585 BAC11074 AK075082 BAC11390 AK093516 BAG52734 AK097387 BAG53462 AK097958 BAC05205 AK225907 AK314526 BAG37120 AY157578 AAO13162 BC010163 AAH10163 BU674771 CA310443 CX784592 DA750046 DQ892670 ABM83596 DR422553 EU176724 ABW03525 NM_022121 NP_071404
Function Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity). {ECO:0000250}.
Subcellular Location Cell junction, desmosome. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Associated with desmosomes. {ECO:0000250}.
Tissue Specificity Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts. {ECO:0000269|PubMed:12752121}.
Top Pathways p53 signaling pathway

Perp CRISPR/Cas9 KO Plasmid (h) - sc-405921 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Perp HDR Plasmid (h) - sc-405921-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Perp Double Nickase Plasmid (h) - sc-405921-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Perp Double Nickase Plasmid (h2) - sc-405921-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Perp CRISPR Activation Plasmid (h) - sc-405921-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Perp CRISPR Activation Plasmid (h2) - sc-405921-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Perp Lentiviral Activation Particles (h) - sc-405921-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Perp Lentiviral Activation Particles (h2) - sc-405921-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Perp siRNA (h) - sc-61326 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Perp shRNA Plasmid (h) - sc-61326-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Perp shRNA (h) Lentiviral Particles - sc-61326-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU119091 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16625 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16625 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PERP siRNA (Human) - CRJ1898 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PERP (NM_022121.4) - SHH373576 from Creative biogene

Category siRNA
Species Reactivities Human

PERP shRNA Plasmid (Human) - CHJ1898 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PERP miRNA 3'UTR clone - MiUTR4H-TG06606 from Creative biogene

Species Reactivities Human
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