INHBC
| Gene Symbol | INHBC |
|---|---|
| Entrez Gene | 3626 |
| Alt Symbol | IHBC |
| Species | Human |
| Gene Type | protein-coding |
| Description | inhibin, beta C |
| Other Description | activin beta-C chain|inhibin beta C chain |
| Swissprots | A1L3Y2 P55103 |
| Accessions | EAW97011 P55103 AK314849 BAG37366 BC020693 BC130324 AAI30325 BC130326 AAI30327 BP237373 BX105206 NM_005538 NP_005529 |
| Function | Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. |
| Subcellular Location | Secreted {ECO:0000250}. |
| Tissue Specificity | Expressed in benign prostatic hyperplasia. {ECO:0000269|PubMed:9428386}. |
| Top Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells |
INHBC-Over-expression-Lysate - LY10407a from Abgent, a WuXi AppTec company
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INHBC overexpression lysate - LY401700 from Acris Antibodies
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Panoply™ Human INHBC Knockdown Stable Cell Line - CSC-DC007650 from Creative biogene
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