Gene Symbol | INHBC |
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Entrez Gene | 3626 |
Alt Symbol | IHBC |
Species | Human |
Gene Type | protein-coding |
Description | inhibin, beta C |
Other Description | activin beta-C chain|inhibin beta C chain |
Swissprots | A1L3Y2 P55103 |
Accessions | EAW97011 P55103 AK314849 BAG37366 BC020693 BC130324 AAI30325 BC130326 AAI30327 BP237373 BX105206 NM_005538 NP_005529 |
Function | Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. |
Subcellular Location | Secreted {ECO:0000250}. |
Tissue Specificity | Expressed in benign prostatic hyperplasia. {ECO:0000269|PubMed:9428386}. |
Top Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells |
Inhibin β-C (C-20) - sc-6888 from Santa Cruz Biotechnology
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Inhibin β-C (T-20) - sc-6889 from Santa Cruz Biotechnology
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Inhibin β-E/C (H-68) - sc-68434 from Santa Cruz Biotechnology
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Anti-Activin (beta C) antibody - ab197692 from Abcam
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Anti-Activin (beta C) antibody - ab135476 from Abcam
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Anti-Activin (beta C) antibody - ab130975 from Abcam
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Anti-Activin (beta C) antibody [betaC clone 1] - ab73904 from Abcam
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Anti-Activin (beta C) antibody - N-terminal - ab178806 from Abcam
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Anti-INHBC Antibody (aa66-115) - LS-C187336 from LifeSpan Bioscience
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Anti-INHBC Antibody (aa237-352) - LS-C294619 from LifeSpan Bioscience
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Anti-INHBC Antibody (aa236-352) - LS-C294616 from LifeSpan Bioscience
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Anti-INHBC Antibody (Val129) - LS-C177515 from LifeSpan Bioscience
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Anti-INHBC Antibody (aa82-113) - LS-C121340 from LifeSpan Bioscience
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Anti-INHBC Antibody (aa82-113, clone betaC clone 1) - LS-C58121 from LifeSpan Bioscience
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Anti-INHBC Antibody (aa82-113) - LS-C121341 from LifeSpan Bioscience
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Anti-INHBC Antibody (aa237-352) - LS-C122593 from LifeSpan Bioscience
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Anti-INHBC Antibody (aa237-352) - LS-C124884 from LifeSpan Bioscience
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Anti-INHBC Antibody (aa235-352) - LS-C294620 from LifeSpan Bioscience
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Anti-INHBC Antibody (aa82-113, clone betaC clone 1) - LS-C188331 from LifeSpan Bioscience
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Anti-INHBC Antibody (aa237-352, Biotin) - LS-C297320 from LifeSpan Bioscience
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Anti-INHBC Antibody (aa235-352, Biotin) - LS-C298817 from LifeSpan Bioscience
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Anti-INHBC Antibody (aa80-129) - LS-C286272 from LifeSpan Bioscience
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Anti-INHBC Antibody (aa236-352, Biotin) - LS-C298812 from LifeSpan Bioscience
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Anti-INHBC Antibody (aa235-352, FITC) - LS-C301724 from LifeSpan Bioscience
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Anti-INHBC Antibody (aa237-352, FITC) - LS-C303520 from LifeSpan Bioscience
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