Gene Symbol | SMYD1 |
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Entrez Gene | 150572 |
Alt Symbol | BOP, KMT3D, ZMYND18, ZMYND22 |
Species | Human |
Gene Type | protein-coding |
Description | SET and MYND domain containing 1 |
Other Description | CD8 beta opposite|SET and MYND domain-containing protein 1|histone-lysine N-methyltransferase SMYD1|zinc finger, MYND domain containing 18 |
Swissprots | A0AV30 Q8NB12 A6NE13 |
Accessions | EAW77077 EAW77078 EAW77079 EAW77080 Q8NB12 AF086123 AK022290 AK091724 BAC03732 AL832035 CAI46139 AY518933 AAT44535 AY518934 AAT44536 BC017915 BC126191 AAI26192 BX647878 CAI46077 EU831908 ACE87349 EU832002 ACE86665 HQ258264 ADR83018 XM_005264156 XP_005264213 NM_198274 NP_938015 |
Function | Methylates histone H3 at 'Lys-4' (H3K4me), seems able to perform both mono-, di-, and trimethylation. Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
Tissue Specificity | Expression seems mostly restricted to heart and skeletal muscle. {ECO:0000269|PubMed:19783823}. |
SMYD1 CRISPR/Cas9 KO Plasmid (h) - sc-406457 from Santa Cruz Biotechnology
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SMYD1 HDR Plasmid (h) - sc-406457-HDR from Santa Cruz Biotechnology
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SMYD1 Double Nickase Plasmid (h) - sc-406457-NIC from Santa Cruz Biotechnology
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SMYD1 Double Nickase Plasmid (h2) - sc-406457-NIC-2 from Santa Cruz Biotechnology
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SMYD1 CRISPR Activation Plasmid (h) - sc-406457-ACT from Santa Cruz Biotechnology
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SMYD1 CRISPR Activation Plasmid (h2) - sc-406457-ACT-2 from Santa Cruz Biotechnology
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SMYD1 Lentiviral Activation Particles (h) - sc-406457-LAC from Santa Cruz Biotechnology
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SMYD1 Lentiviral Activation Particles (h2) - sc-406457-LAC-2 from Santa Cruz Biotechnology
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SMYD1 siRNA (h) - sc-76527 from Santa Cruz Biotechnology
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SMYD1 shRNA Plasmid (h) - sc-76527-SH from Santa Cruz Biotechnology
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SMYD1 shRNA (h) Lentiviral Particles - sc-76527-V from Santa Cruz Biotechnology
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SmyD1 RNAi - H00150572-R01 from Novus Biologicals
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MISSION® esiRNA - EHU047561 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19815 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19815 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR11803 from Sigma-Aldrich
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SMYD1 siRNA (Human) - CRJ5664 from Cohesion Biosciences
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SMYD1 - MBS827980 from MyBioSource
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shRNA set against Human SMYD1 (NM_198274.3) - SHH413764 from Creative biogene
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Human SMYD1 siRNA - orb276165 from Biorbyt
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SMYD1 shRNA Plasmid (Human) - CHJ5664 from Cohesion Biosciences
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