| Gene Symbol |
KIF2B
|
| Entrez Gene |
84643
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
kinesin family member 2B
|
| Other Description |
kinesin protein|kinesin-like protein KIF2B
|
| Swissprots |
Q8N4N8 Q9BXG6 Q96MA2
|
| Accessions |
CBH19335 CBH30642 EAW94554 Q8N4N8 AF333335 AAK20830 AK057272 BAB71406 AK302262 BAG63610 AK308265 BC033802 AAH33802 DB457485 JF432265 ADZ15482 NM_032559 NP_115948
|
| Function |
Plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement. Has microtubule depolymerization activity. {ECO:0000269|PubMed:17538014}.
|
| Subcellular Location |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:17538014}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:17538014}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:17538014}. Note=Association with kinetochore is transient.
|
| Tissue Specificity |
Highest level in lung. High level in ovary, moderate levels in heart, kidney, placenta, skeletal muscle and spleen (at protein level). Pancreas and spleen express a shorter isoform (at protein level). {ECO:0000269|PubMed:17538014}.
|