Gene Symbol | KIF2B |
---|---|
Entrez Gene | 84643 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | kinesin family member 2B |
Other Description | kinesin protein|kinesin-like protein KIF2B |
Swissprots | Q8N4N8 Q9BXG6 Q96MA2 |
Accessions | CBH19335 CBH30642 EAW94554 Q8N4N8 AF333335 AAK20830 AK057272 BAB71406 AK302262 BAG63610 AK308265 BC033802 AAH33802 DB457485 JF432265 ADZ15482 NM_032559 NP_115948 |
Function | Plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement. Has microtubule depolymerization activity. {ECO:0000269|PubMed:17538014}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:17538014}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:17538014}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:17538014}. Note=Association with kinetochore is transient. |
Tissue Specificity | Highest level in lung. High level in ovary, moderate levels in heart, kidney, placenta, skeletal muscle and spleen (at protein level). Pancreas and spleen express a shorter isoform (at protein level). {ECO:0000269|PubMed:17538014}. |