Gene Symbol | KIF2B |
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Entrez Gene | 84643 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | kinesin family member 2B |
Other Description | kinesin protein|kinesin-like protein KIF2B |
Swissprots | Q8N4N8 Q9BXG6 Q96MA2 |
Accessions | CBH19335 CBH30642 EAW94554 Q8N4N8 AF333335 AAK20830 AK057272 BAB71406 AK302262 BAG63610 AK308265 BC033802 AAH33802 DB457485 JF432265 ADZ15482 NM_032559 NP_115948 |
Function | Plus end-directed microtubule-dependent motor required for spindle assembly and chromosome movement. Has microtubule depolymerization activity. {ECO:0000269|PubMed:17538014}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:17538014}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:17538014}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:17538014}. Note=Association with kinetochore is transient. |
Tissue Specificity | Highest level in lung. High level in ovary, moderate levels in heart, kidney, placenta, skeletal muscle and spleen (at protein level). Pancreas and spleen express a shorter isoform (at protein level). {ECO:0000269|PubMed:17538014}. |
KIF2B CRISPR/Cas9 KO Plasmid (h) - sc-413680 from Santa Cruz Biotechnology
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KIF2B HDR Plasmid (h) - sc-413680-HDR from Santa Cruz Biotechnology
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KIF2B Double Nickase Plasmid (h) - sc-413680-NIC from Santa Cruz Biotechnology
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KIF2B Double Nickase Plasmid (h2) - sc-413680-NIC-2 from Santa Cruz Biotechnology
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KIF2B CRISPR Activation Plasmid (h) - sc-413680-ACT from Santa Cruz Biotechnology
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KIF2B CRISPR Activation Plasmid (h2) - sc-413680-ACT-2 from Santa Cruz Biotechnology
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KIF2B Lentiviral Activation Particles (h) - sc-413680-LAC from Santa Cruz Biotechnology
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KIF2B Lentiviral Activation Particles (h2) - sc-413680-LAC-2 from Santa Cruz Biotechnology
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KIF2B siRNA (h) - sc-94083 from Santa Cruz Biotechnology
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KIF2B shRNA Plasmid (h) - sc-94083-SH from Santa Cruz Biotechnology
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KIF2B shRNA (h) Lentiviral Particles - sc-94083-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU130411 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11197 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11197 from Sigma-Aldrich
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KIF2B siRNA (Human) - CRJ3552 from Cohesion Biosciences
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shRNA set against Human KIF2B (NM_032559.4) - SHH325259 from Creative biogene
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shRNA set against Human KIF2B(NM_032559.4) - SHL197002 from Creative biogene
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KIF2B shRNA Plasmid (Human) - CHJ3552 from Cohesion Biosciences
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KIF2B miRNA 3'UTR clone - MiUTR1H-05311 from Creative biogene
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