DOK1

Gene Symbol	DOK1
Entrez Gene	1796
Alt Symbol	P62DOK
Species	Human
Gene Type	protein-coding
Description	docking protein 1, 62kDa (downstream of tyrosine kinase 1)
Other Description	Downstream of tyrosine kinase 1|docking protein 1|docking protein 1 (downstream of tyrosine kinase 1)|p62(dok)|pp62
Swissprots	Q53TY2 O43204 Q99704 Q9UHG6
Accessions	AAX93224 EAW99612 EAW99613 EAW99614 Q99704 AF035299 AAB88182 AF180527 AAF19167 AK055944 BAG51595 AK127127 BAG54440 AK127656 BAG54544 AK222883 BAD96603 AK296154 BAG58893 AK300097 BAG61898 AK314678 BC111055 AAI11056 BC114440 AAI14441 BC114497 AAI14498 BQ575925 DA382785 DA599419 U70987 AAC51127 XM_011532669 XP_011530971 XM_011532670 XP_011530972 NM_001197260 NP_001184189 NM_001381 NP_001372
Function	DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3. {ECO:0000269|PubMed:18156175}.
Subcellular Location	Isoform 1: Cytoplasm. Nucleus.
Tissue Specificity	Expressed in pancreas, heart, leukocyte and spleen. Expressed in both resting and activated peripheral blood T-cells. Expressed in breast cancer. {ECO:0000269|PubMed:12595900}.
Top Pathways	Measles

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human/Rat Phospho-DOK1 (Tyr362) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1485 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate

Mouse/Human/Rat Phospho-DOK1 (Tyr398) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1486 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate

Mouse/Human/Rat DOK1 ELISA Kit (Cell-Based ELISA) - LS-F2213 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate

p62 Dok Colorimetric Cell-Based ELISA Kit - CB5521 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

p62 Dok (Phospho-Tyr362) Colorimetric Cell-Based ELISA Kit - CBP1529 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

p62 Dok (Phospho-Tyr398) Colorimetric Cell-Based ELISA Kit - CBP1530 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Docking Protein 1 (DOK1), ELISA Kit - MBS9311731 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

docking protein 1, 62kDa (downstream of tyrosine kinase 1) , ELISA Kit - MBS9336141 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Phospho-p62Dok Antibody Panel - ARG30188 from Arigo Biolaboratories Category Antibody Pair

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