Gene Symbol | Amer2 |
---|---|
Entrez Gene | 72125 |
Alt Symbol | 2600011E07Rik, Fam123a |
Species | Mouse |
Gene Type | protein-coding |
Description | APC membrane recruitment 2 |
Other Description | APC membrane recruitment protein 2|family with sequence similarity 123, member A|protein FAM123A |
Swissprots | Q8CCJ4 Q7TNC5 Q9D0Q2 Q8K0U9 |
Accessions | Q8CCJ4 AK011185 BAB27452 AK032651 BAC27972 AK139177 BAE23912 BC030356 AAH30356 BC056350 AAH56350 CJ122740 XM_006519590 XP_006519653 XM_006519591 XP_006519654 NM_001164705 NP_001158177 NM_028113 NP_082389 |
Function | Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Translocates to the cell membrane following binding to PtdIns(4,5)P2. {ECO:0000250}. |
Anti-AMER2 Antibody (N-Terminus) - LS-C146356 from LifeSpan Bioscience
|
||||||||
Anti-FAM123A antibody produced in rabbit - SAB2107123 from Sigma-Aldrich
|
||||||||
Fam123a antibody - N-terminal region (ARP55491_P050) - ARP55491_P050 from Aviva Systems Biology
|
||||||||
Fam123a Antibody - GWB-MT876C from Genway Biotech
|
||||||||
Anti-AMER2 (aa 2-51) polyclonal antibody - DPABH-28356 from Creative Diagnostics
|
||||||||
Fam123a-antibody-N-terminal-region-AI13805 - AI13805 from Abgent, a WuXi AppTec company
|
||||||||
Anti-FAM123A antibody produced in rabbit - SAB2108425 from Sigma-Aldrich
|
||||||||
Fam123a antibody - N-terminal region : Biotin (ARP55491_P050-Biotin) - ARP55491_P050-Biotin from Aviva Systems Biology
|
||||||||
Fam123a antibody - N-terminal region : FITC (ARP55491_P050-FITC) - ARP55491_P050-FITC from Aviva Systems Biology
|
||||||||
Fam123a antibody - N-terminal region : HRP (ARP55491_P050-HRP) - ARP55491_P050-HRP from Aviva Systems Biology
|
||||||||
Anti-AMER2 Antibody (N-Terminus, Biotin) - LS-C460255 from LifeSpan Bioscience
|
||||||||
Anti-AMER2 Antibody (N-Terminus, FITC) - LS-C460256 from LifeSpan Bioscience
|
||||||||
Anti-AMER2 Antibody (N-Terminus, HRP) - LS-C460257 from LifeSpan Bioscience
|
||||||||