ADRA1B

Gene Symbol	ADRA1B
Entrez Gene	147
Alt Symbol	ADRA1, ALPHA1BAR
Species	Human
Gene Type	protein-coding
Description	adrenoceptor alpha 1B
Other Description	adrenergic, alpha-1B-, receptor|alpha-1B adrenergic receptor|alpha-1B adrenoceptor|alpha-1B adrenoreceptor|alpha-1B-adrenergic receptor
Swissprots	B0LPE1 P35368
Accessions	AAS21324 ABY87520 EAW61572 P35368 AK309989 BC136568 AAI36569 BC136569 AAI36570 BQ576306 BX648936 L31773 AAB59485 U03865 AAB60352 XM_005265818 XP_005265875 XM_005265819 XP_005265876 XM_006714821 XP_006714884 XM_011534435 XP_011532737 XM_011534436 XP_011532738 XM_011534437 XP_011532739 XM_011534438 XP_011532740 XM_011534439 XP_011532741 XM_011534440 XP_011532742 NM_000679 NP_000670
Function	This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes. {ECO:0000269|PubMed:18802028, ECO:0000269|PubMed:22120526}.
Subcellular Location	Nucleus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Location at the nuclear membrane facilitates heterooligomerization and regulates ERK-mediated signaling in cardiac myocytes. signaling in cardiac myocytes. Colocalizes with GNAQ, PLCB1 as well as LAP2 at the nuclear membrane of cardiac myocytes.
Top Pathways	Calcium signaling pathway, Vascular smooth muscle contraction, Salivary secretion, Adrenergic signaling in cardiomyocytes, cGMP-PKG signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ADRA1B Antibody Blocking Peptide - LS-E21955 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ADRA1B Antibody Blocking Peptide - LS-E21954 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ADRA1B Antibody Blocking Peptide - LS-E29207 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ADRA1B Antibody Blocking Peptide - LS-E29208 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ADRA1B Antibody Blocking Peptide - LS-E29209 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ADRA1B Antibody Blocking Peptide - LS-E29210 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

ADRA1B Antibody Blocking Peptide - LS-E10111 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ADRA1B Antibody Blocking Peptide - LS-E28029 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ADRA1B Antibody Blocking Peptide - LS-E28030 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

ADRA1B-Antibody-Center-Blocking-Peptide - BP9404c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

ADRA1B Blocking Peptide - 33R-9914 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

ADRA1B Blocking Peptide - 33R-10230 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Alpha-1B Adrenergic Receptor Blocking Peptide - abx062220 from Abbexa Category Peptide Species Human, Rat

Alpha 1b Adrenergic Receptor Peptide - AC21-2788-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Alpha 1b Adrenergic Receptor Peptide - AC21-2789-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ADRA1B fusion protein - ag18138 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ADRA1B fusion protein - Ag19326 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Alpha 1b-Adrenoceptor (ADRA1B) - GWB-C20EED from Genway Biotech Category Peptide Prices $161.00 Sizes 50 µl Species Human

ChemiSCREEN™ Membrane Preparation Recombinant Human α 1B Adrenergic Receptor - HTS158M from EMD Millipore Prices $596.00 Sizes 200 units Species Human

Alpha-1B Adrenergic Receptor Blocking Peptide - CBP1026 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Rat

AR-α1B Peptide - BS5622P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Alpha-1B adrenergic receptor (ADRA1B) - MBS1093610 from MyBioSource Category Protein Prices $1,065.00, $1,065.00, $1,520.00, $1,520.00 Sizes 1 mg (E Coli Derived), 100 µg (Baculovirus Derived), 1 mg (Yeast Derived), 100 µg (Mammalian Cell Derived) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Wheat

Alpha-1D adrenergic receptor (Adra1d) - MBS955211 from MyBioSource Category Protein Prices $1,375.00, $1,835.00 Sizes 1 mg (E Coli Derived), 1 mg (Yeast Derived) Source E Coli or Yeast Species Human

ADRA1B Peptide - abx164832 from Abbexa Category Peptide Species Human, Mouse, Rat

ADRA1B Peptide - abx164667 from Abbexa Category Peptide Species Human, Mouse, Rat

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