Gene Symbol | METTL21A |
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Entrez Gene | 151194 |
Alt Symbol | FAM119A, HCA557b, HSPA-KMT |
Species | Human |
Gene Type | protein-coding |
Description | methyltransferase like 21A |
Other Description | HSPA lysine methyltransferase|family with sequence similarity 119, member A|heat shock protein 70kDa lysine (K) methyltransferase|hepatocellular carcinoma-associated antigen 557b|methyltransferase-like protein 21A|protein N-lysine methyltransferase METTL21A|protein-lysine methyltransferase METTL21A |
Swissprots | Q8WXB1 Q96GH6 Q53RV0 Q8N1Z9 |
Accessions | AAX93175 EAW70411 EAW70412 EAW70413 EAW70414 EAW70415 EAW70416 EAW70417 Q8WXB1 AF455817 AAL66295 AI332764 AI363134 AK093812 BAC04229 BC009462 AAH09462 BC033720 AAH33720 BG198655 BG832122 CN367990 XM_005246336 XP_005246393 XM_005246337 XP_005246394 XM_005246338 XP_005246395 XM_005246339 XP_005246396 XM_005246340 XP_005246397 XM_005246341 XP_005246398 XM_006712327 XP_006712390 XM_006712329 XP_006712392 XM_011510724 XP_011509026 XM_011510725 XP_011509027 XM_011510726 XP_011509028 XM_011510727 XP_011509029 XM_011510728 XP_011509030 XM_011510729 XP_011509031 XM_011510730 XP_011509032 XM_011510731 XP_011509033 XM_011510732 XP_011509034 NM_001127395 NP_001120867 NM_001308021 NP_001294950 NM_145280 NP_660323 |
Function | Protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members. Contributes to the in vivo trimethylation of Lys residues in HSPA1 and HSPA8. In vitro methylates 'Lys-561' in HSPA1, 'Lys- 564' in HSPA2, 'Lys-585' in HSPA5, 'Lys-563' in HSPA6 and 'Lys- 561' in HSPA8. {ECO:0000269|PubMed:22948820, ECO:0000269|PubMed:23349634, ECO:0000269|PubMed:23921388}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:23349634}. |
Human FAM119A full length protein - ab165621 from Abcam
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Human FAM119A protein fragment - ab167907 from Abcam
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HCA557B / METTL21A Antibody Blocking Peptide - LS-E19042 from LifeSpan Bioscience
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HCA557B / METTL21A Antibody Blocking Peptide - LS-E19043 from LifeSpan Bioscience
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FAM119A Recombinant Protein - H00151194-P01 from Novus Biologicals
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FAM119A Protein - NBP2-23232 from Novus Biologicals
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FAM119A-Antibody-C-term-Blocking-peptide - BP12681b from Abgent, a WuXi AppTec company
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Human METTL21A Enzyme - orb191425 from Biorbyt
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FAM119A Blocking Peptide - 33R-4961 from Fitzgerald
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FAM119A Blocking Peptide - 33R-1379 from Fitzgerald
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METTL21A protein (His tag) - 80R-2868 from Fitzgerald
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FAM119A (93-218, His-tag) - AR50987PU-N from Acris Antibodies
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FAM119A (93-218, His-tag) - AR50987PU-S from Acris Antibodies
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FAM119A - H00151194-P01-10 from Acris Antibodies
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FAM119A - H00151194-P01-25 from Acris Antibodies
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METTL21A, 93-218aa, Human, His tag, E.coli - 01-P2163 from ARP American Research Products
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FAM119A fusion protein - Ag15282 from Proteintech Group
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FAM119A fusion protein - ag15481 from Proteintech Group
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Recombinant Human FAM119A, GST-tagged - FAM119A-12661H from Creative Biomart
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Recombinant Human methyltransferase like 21A, His-tagged - METTL21A-209H from Creative Biomart
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Recombinant Human Methyltransferase-like protein 21A(METTL21A) - CSB-YP845165HU CSB-EP845165HU CSB-BP845165HU CSB-MP845165HU from Cusabio
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METTL21A, 93-218aa, Human, His tag, E.coli - ATGP2163 from ATGen
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FAM119A (transcript variant 1) - TP307629 from Acris Antibodies
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FAM119A (full length, N-term HIS tag, transcript variant 2) - TP760710 from Acris Antibodies
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