Gene Symbol | METTL21A |
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Entrez Gene | 151194 |
Alt Symbol | FAM119A, HCA557b, HSPA-KMT |
Species | Human |
Gene Type | protein-coding |
Description | methyltransferase like 21A |
Other Description | HSPA lysine methyltransferase|family with sequence similarity 119, member A|heat shock protein 70kDa lysine (K) methyltransferase|hepatocellular carcinoma-associated antigen 557b|methyltransferase-like protein 21A|protein N-lysine methyltransferase METTL21A|protein-lysine methyltransferase METTL21A |
Swissprots | Q8WXB1 Q96GH6 Q53RV0 Q8N1Z9 |
Accessions | AAX93175 EAW70411 EAW70412 EAW70413 EAW70414 EAW70415 EAW70416 EAW70417 Q8WXB1 AF455817 AAL66295 AI332764 AI363134 AK093812 BAC04229 BC009462 AAH09462 BC033720 AAH33720 BG198655 BG832122 CN367990 XM_005246336 XP_005246393 XM_005246337 XP_005246394 XM_005246338 XP_005246395 XM_005246339 XP_005246396 XM_005246340 XP_005246397 XM_005246341 XP_005246398 XM_006712327 XP_006712390 XM_006712329 XP_006712392 XM_011510724 XP_011509026 XM_011510725 XP_011509027 XM_011510726 XP_011509028 XM_011510727 XP_011509029 XM_011510728 XP_011509030 XM_011510729 XP_011509031 XM_011510730 XP_011509032 XM_011510731 XP_011509033 XM_011510732 XP_011509034 NM_001127395 NP_001120867 NM_001308021 NP_001294950 NM_145280 NP_660323 |
Function | Protein-lysine methyltransferase that selectively trimethylates residues in heat shock protein 70 (HSP70) family members. Contributes to the in vivo trimethylation of Lys residues in HSPA1 and HSPA8. In vitro methylates 'Lys-561' in HSPA1, 'Lys- 564' in HSPA2, 'Lys-585' in HSPA5, 'Lys-563' in HSPA6 and 'Lys- 561' in HSPA8. {ECO:0000269|PubMed:22948820, ECO:0000269|PubMed:23349634, ECO:0000269|PubMed:23921388}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:23349634}. |
METTL21A (C-12) - sc-240381 from Santa Cruz Biotechnology
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Anti-FAM119A antibody [2D6] - ab119186 from Abcam
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Anti-HCA557B / METTL21A Antibody (N-Terminus) - LS-C102481 from LifeSpan Bioscience
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Anti-HCA557B / METTL21A Antibody (aa72-121) - LS-C102482 from LifeSpan Bioscience
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Anti-HCA557B / METTL21A Antibody (clone 2D6) - LS-C173386 from LifeSpan Bioscience
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Anti-HCA557B / METTL21A Antibody (clone 1C8) - LS-C337550 from LifeSpan Bioscience
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Anti-HCA557B / METTL21A Antibody (clone 2D3) - LS-C173448 from LifeSpan Bioscience
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Anti-HCA557B / METTL21A Antibody (clone 2G7) - LS-C173387 from LifeSpan Bioscience
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FAM119A Antibody (2G7) - NBP2-01334 from Novus Biologicals
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FAM119A Antibody - NBP1-83282 from Novus Biologicals
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FAM119A Antibody - NBP1-56655 from Novus Biologicals
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Anti-FAM119A (ab2) antibody produced in rabbit - SAB2100750 from Sigma-Aldrich
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Anti-FAM119A (6-20) antibody produced in rabbit - SAB1103268 from Sigma-Aldrich
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Anti-METTL21A antibody produced in rabbit - HPA034712 from Sigma-Aldrich
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FAM119A antibody - N-terminal region (ARP52843_P050) - ARP52843_P050 from Aviva Systems Biology
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FAM119A antibody - middle region (ARP52844_P050) - ARP52844_P050 from Aviva Systems Biology
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FAM119A antibody, Internal - GTX45687 from GeneTex
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FAM119A antibody, N-term - GTX45688 from GeneTex
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METTL21A antibody - 10R-4802 from Fitzgerald
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METTL21A antibody - 10R-4800 from Fitzgerald
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METTL21A antibody - 10R-4801 from Fitzgerald
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FAM119A antibody - 70R-17207 from Fitzgerald
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FAM119A antibody - 70R-3148 from Fitzgerald
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FAM119A antibody - 70R-3617 from Fitzgerald
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Family With Sequence Similarity 119, Member A Antibody - abx112430 from Abbexa
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