SOX2

Gene Symbol	SOX2
Entrez Gene	6657
Alt Symbol	ANOP3, MCOPS3
Species	Human
Gene Type	protein-coding
Description	SRY (sex determining region Y)-box 2
Other Description	SRY-related HMG-box gene 2|transcription factor SOX-2|transcription factor SOX2
Swissprots	Q14537 P48431
Accessions	AJF45877 AJF45878 AJF45879 AJF45880 AJF45899 AJF45900 AJF45901 AJF45902 AJF45903 AJF45904 AJF45905 AJF45906 AJF45907 AJF45908 AJF45909 AJF45910 AJF45911 AJF45912 EAW78354 P48431 AK312595 BAG35487 AW016610 AW163619 BC013923 AAH13923 BF305585 BM668019 BM722297 CN430685 DA388996 EU446654 ABZ92183 KM822781 AJF45876 L07335 AAA35997 Z31560 CAA83435 NM_003106 NP_003097
Function	Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). {ECO:0000250}.
Subcellular Location	Nucleus.
Top Pathways	Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human SOX2 full length protein - ab169843 from Abcam Category Protein Prices $239.00 Sizes 50 µg Source E. coli Species Human

Human SOX2 full length protein - ab95847 from Abcam Category Protein Source E. coli Species Human

Human SOX2 full length protein - ab79950 from Abcam Category Protein Source E. coli Species Human

Human SOX2 full length protein - ab80520 from Abcam Category Protein Source E. coli Species Human

Human SOX2 peptide - ab15831 from Abcam Category Peptide

Human SOX2 peptide - ab97974 from Abcam Category Peptide

Human SOX2 protein fragment - ab93948 from Abcam Category Protein Source E. coli Species Human

Mouse SOX2 peptide - ab157771 from Abcam Category Peptide

SOX2 (glcnac S248) peptide - ab157602 from Abcam Category Peptide

SOX2 Antibody Blocking Peptide - LS-E6832 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SOX2 Antibody Blocking Peptide - LS-E30853 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

SOX2 Antibody Blocking Peptide - LS-E7485 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SOX2 Antibody Blocking Peptide - LS-E11087 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SOX2 Antibody Blocking Peptide - LS-E13729 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

SOX2 Antibody Blocking Peptide - LS-E13730 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Human SOX2 TAT Protein - NBP2-35268 from Novus Biologicals Category Protein Prices $75.00 Sizes 5 µg Species Human

SOX2 Blocking Peptide - NB110-37235PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg Species Human

SOX2 Recombinant Protein - H00006657-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

SOX2 Partial Recombinant Protein - H00006657-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human SOX2 Protein - NBP1-41144 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E. coli Species Human

SOX2 Peptide - P0843 from Novus Biologicals Category Peptide Species Human

SOX2-Antibody-N-term-Blocking-Peptide - BP2048d from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Phospho-SOX2S83-Antibody-Blocking-peptide - BP3651a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

phospho-Sox2S246-Antibody-Blocking-peptide - BP3750a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

phospho-Sox2S251-Antibody-Blocking-peptide - BP3742a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

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