PRSS8

Gene Symbol PRSS8
Entrez Gene 5652
Alt Symbol CAP1, PROSTASIN
Species Human
Gene Type protein-coding
Description protease, serine, 8
Other Description channel-activating protease 1|prostasin|serine protease 8
Swissprots B4DWP2 Q16651 Q9UCA3
Accessions AAB19071 EAW52155 EAW52156 Q16651 AK296656 BAG59253 AK301619 BAG63104 AK309955 BC001462 AAH01462 DQ892160 ABM83086 DQ895354 ABM86280 L41351 AAC41759 NM_002773 NP_002764
Function Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G). {ECO:0000269|PubMed:15246975, ECO:0000269|PubMed:15474520}.
Subcellular Location Prostasin heavy chain: Secreted, extracellular space. Note=Found in the seminal fluid. Secreted after cleavage of its C-terminus.
Tissue Specificity Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid.

Prostasin (M-52) - sc-98859 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Prostasin (M-52): sc-98859. Western blot analysis of Prostasin expression in Hep G2 whole cell lysate.

Prostasin (N-12) - sc-27594 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Prostasin (H-75) - sc-98868 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Prostasin (H-75): sc-98868. Western blot analysis of Prostasin expression in non-transfected: sc-117752 (A) and human Prostasin transfected: sc-170169 (B) 293T whole cell lysates.

Prostasin (K-15) - sc-27591 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Prostasin (2) - sc-136272 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
Prostasin (2): sc-136272. Western blot analysis of Prostasin expression in LNCaP-FGC-10 whole cell lysate.

Anti-PRSS8 antibody - ab200736 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PRSS8 antibody (ab200736)Lane 1 : HEK293T whole cell lysateLane 2 : RAW 264.7 whole cell lysateLane 3 : PC12 whole cell lysate

Anti-PRSS8 antibody - ab59492 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PRSS8 antibody (ab59492) at 1/1000 dilutionLane 1 : Recombinant Mouse Prostasin at 0.08 µgLane 2 : Recombinant Mouse Prostasin at 0.04 µgLane 3 : Recombinant Mouse Prostasin at 0.02 µgLane 4 : Recombinant Mouse Prostasin at 0.01 µgLane 5 : Recombinant Mouse Prostasin at 0.005 µg

Anti-PRSS8 antibody - ab59494 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PRSS8 antibody (ab59494) at 1/1000 dilutionLane 1 : Recombinant Mouse Prostasin at 0.08 µgLane 2 : Recombinant Mouse Prostasin at 0.04 µgLane 3 : Recombinant Mouse Prostasin at 0.02 µgLane 4 : Recombinant Mouse Prostasin at 0.01 µgLane 5 : Recombinant Mouse Prostasin at 0.005 µg

Anti-PRSS8 antibody - ab59496 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PRSS8 antibody (ab59496) at 1/1000 dilutionLane 1 : Recombinant Mouse Prostasin at 0.08 µgLane 2 : Recombinant Mouse Prostasin at 0.04 µgLane 3 : Recombinant Mouse Prostasin at 0.02 µgLane 4 : Recombinant Mouse Prostasin at 0.01 µgLane 5 : Recombinant Mouse Prostasin at 0.005 µg

Anti-PRSS8 antibody - ab59499 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PRSS8 antibody (ab59499) at 1/1000 dilutionLane 1 : Cell media from human prostate adenocarcinoma (LNCaP) cell line (treated with TPA) Lane 2 : Cell media from human prostate adenocarcinoma (LNCaP) cell line (treated with IL1-alpha) Lysates/proteins at 40 µl per lane.

Anti-PRSS8 antibody - ab167373 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-PRSS8 antibody (ab167373) at 1 µg/mlLane 1 : PRSS8 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-PRSS8 antibody [EPR15327] - ab185236 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR15327
Western blot analysis of immunoprecipitation pellet from MCF7 cell lysate, immunoprecipitated using ab185235 at 1/50 dilution (lane 1) or PBS control (lane 2).Secondary: Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1500 dilution.

Anti-PRSS8 / Prostasin Antibody (aa30-339, FITC) - LS-C304806 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PRSS8 / Prostasin Antibody (aa33-272, FITC) - LS-C305158 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PRSS8 / Prostasin Antibody (aa189-219) - LS-C324339 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRSS8 / Prostasin Antibody (aa143-192) - LS-C116638 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PRSS8 antibody LS-C116638 Western blot of Jurkat lysate.

Anti-PRSS8 / Prostasin Antibody (aa124-342) - LS-C296079 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant PRSS8 / Prostasin.

Anti-PRSS8 / Prostasin Antibody (aa124-342) - LS-C296080 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant PRSS8 / Prostasin.

Anti-PRSS8 / Prostasin Antibody (aa30-339) - LS-C296081 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant PRSS8 / Prostasin.

Anti-PRSS8 / Prostasin Antibody (aa189-219) - LS-C162200 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PRSS8 Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The PRSS8 antibody detected the PRSS8 protein (arrow).

Anti-PRSS8 / Prostasin Antibody (aa33-272) - LS-C296078 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant PRSS8 / Prostasin.

Anti-PRSS8 / Prostasin Antibody (clone 3C4) - LS-C198013 from LifeSpan Bioscience

Prices $355.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 3C4
PRSS8 monoclonal antibody (M11A), clone 3C4. Western Blot analysis of PRSS8 expression in NIH/3T3.

Anti-PRSS8 / Prostasin Antibody - LS-C131616 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-PRSS8 / Prostasin Antibody (aa189-219, AP) - LS-C267236 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRSS8 / Prostasin Antibody (aa189-219, APC) - LS-C267237 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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