PRSS8

Gene Symbol	PRSS8
Entrez Gene	5652
Alt Symbol	CAP1, PROSTASIN
Species	Human
Gene Type	protein-coding
Description	protease, serine, 8
Other Description	channel-activating protease 1|prostasin|serine protease 8
Swissprots	B4DWP2 Q16651 Q9UCA3
Accessions	AAB19071 EAW52155 EAW52156 Q16651 AK296656 BAG59253 AK301619 BAG63104 AK309955 BC001462 AAH01462 DQ892160 ABM83086 DQ895354 ABM86280 L41351 AAC41759 NM_002773 NP_002764
Function	Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. Stimulates epithelial sodium channel (ENaC) activity through activating cleavage of the gamma subunits (SCNN1G). {ECO:0000269|PubMed:15246975, ECO:0000269|PubMed:15474520}.
Subcellular Location	Prostasin heavy chain: Secreted, extracellular space. Note=Found in the seminal fluid. Secreted after cleavage of its C-terminus.
Tissue Specificity	Found in prostate, liver, salivary gland, kidney, lung, pancreas, colon, bronchus and renal proximal tubular cells. In the prostate gland it may be synthesized in epithelial cells, secreted into the ducts, and excreted into the seminal fluid.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Prostasin CRISPR/Cas9 KO Plasmid (h) - sc-405775 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Prostasin HDR Plasmid (h) - sc-405775-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Prostasin Double Nickase Plasmid (h) - sc-405775-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Prostasin Double Nickase Plasmid (h2) - sc-405775-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Prostasin CRISPR Activation Plasmid (h) - sc-405775-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Prostasin CRISPR Activation Plasmid (h2) - sc-405775-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Prostasin Lentiviral Activation Particles (h) - sc-405775-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Prostasin Lentiviral Activation Particles (h2) - sc-405775-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Prostasin siRNA (h) - sc-63314 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Prostasin shRNA Plasmid (h) - sc-63314-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Prostasin shRNA (h) Lentiviral Particles - sc-63314-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU005521 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17551 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17551 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR04817 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr04817

PRSS8 siRNA (Human) - CRH3810 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

Prostasin/Prss8 RNAi - H00005652-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

shRNA set against Human PRS (NM_002773.3) - SHH384316 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human PRSS8(NM_002773.3) - SHG139573 from Creative biogene Category siRNA Species Reactivities Human

Prostasin CRISPR/Cas9 KO Plasmid (h2) - sc-405775-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Prostasin HDR Plasmid (h2) - sc-405775-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Human PRSS8 siRNA - orb264312 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

PRSS8 shRNA Plasmid (Human) - CHH3810 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

PRSS8 miRNA 3'UTR clone - MiUTR1H-08341 from Creative biogene Species Reactivities Human

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