TFDP2

Gene Symbol TFDP2
Entrez Gene 7029
Alt Symbol DP2
Species Human
Gene Type protein-coding
Description transcription factor Dp-2 (E2F dimerization partner 2)
Other Description transcription factor Dp-2
Swissprots Q14188 Q14187 Q13331 D3DNG1 Q9UG28 B7Z8L5 E9PFC3 F8WAI2 B7Z8C8 Q6R754 Q8WU88
Accessions AAR89905 EAW78977 EAW78978 EAW78979 EAW78980 EAW78981 Q14188 AB528993 BAI47157 AK096450 AK303181 BAH13914 AK303634 BAH14001 AK314786 AL080206 CAB45775 AW673504 BC007976 BC013993 BC021113 AAH21113 BC040991 BX647881 CU676832 CU676833 DA321332 DC319314 EU446663 ABZ92192 HG496116 L40386 AAA69016 U18422 AAB60378 U35117 AAC50642 XM_005247731 XP_005247788 XM_011513101 XP_011511403 XM_011513102 XP_011511404 XM_011513103 XP_011511405 XM_011513104 XP_011511406 XM_011513105 XP_011511407 XM_011513106 XP_011511408 XM_011513107 XP_011511409 XM_011513108 XP_011511410 XM_011513109 XP_011511411 XM_011513110 XP_011511412 XM_011513111 XP_011511413 NM_001178138 NP_001171609 NM_001178139 NP_001171610 NM_001178140 NP_001171611 NM_001178141 NP_001171612 NM_001178142 NP_001171613 NM_006286 NP_006277
Function Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The TFDP2:E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812). {ECO:0000305|PubMed:20176812}.
Subcellular Location Nucleus.
Tissue Specificity High levels in heart and skeletal muscle. Also found in placenta, kidney, brain, lung and liver. The presence as well as the abundance of the different transcripts appear to vary significantly in different tissues and cell lines.
Top Pathways Cell cycle

DP-2 (D-11) - sc-374614 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DP-2 (D-11): sc-374614. Western blot analysis of DP-2 expression in A-431 (A), Hep G2 (B) and KNRK (C) nuclear extracts.

DP-2 (C-20) - sc-829 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
DP-2 (C-20): sc-829. Western blot analysis of human recombinant DP-2 fusion protein.

DP-2 (FL-386) - sc-1209 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
DP-2 (FL-386): sc-1209. Western blot analysis of human recombinant DP-2 fusion protein.

DP-2 (N-20) - sc-830 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
DP-2 (N-20): sc-830. Western blot analysis of DP-2 expression in KNRK nuclear extract.

DP-2 (G-12) - sc-6849 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
DP-2 (G-12): sc-6849. Western blot analysis of human recombinant DP-2 fusion protein.

Anti-DP2 antibody - ab155246 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-DP2 antibody (ab155246) at 1/1000 dilution + Mouse muscle whole cell lysate at 50 µg

Anti-DP2 antibody - ab26260 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-DP2 antibody (ab26260) at 1.25 µg/ml + Jurkat cell lysateSecondaryHRP conjugated anti-Rabbit IgG diluted 1/50000 - 1/100000

Anti-DP2 antibody - ab44995 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-DP2 antibody - ab135847 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-DP2 antibody (ab135847) at 1/500 dilution + extracts from COS7 cells

Anti-DP2 antibody [BC-2] - ab11835 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone BC-2

Anti-DP2 antibody [TFD5I455] - ab50882 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone TFD5I455
Anti-DP2 antibody [TFD5I455] (ab50882) + immunizing peptide

Anti-TFDP2 / DP2 Antibody - LS-C76483 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-TFDP2 / DP2 Antibody (clone TFD5I455) - LS-C184249 from LifeSpan Bioscience

Prices $335.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone TFD5I455

Anti-GPR44 / CRTH2 Antibody (Asp113) - LS-C177245 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of DP-2 (D113) pAb in extracts from COS7 cells.

Anti-TFDP2 / DP2 Antibody (aa301-350) - LS-C116128 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TFDP2 / Dp-2 antibody LS-C116128 Western blot of Mouse Uterus lysate.

Anti-TFDP2 / DP2 Antibody (N-Terminus) - LS-C30921 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
TFDP2 / Dp-2 antibody LS-C30921 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-TFDP2 / DP2 Antibody (aa51-100) - LS-C170173 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-TFDP2 / DP2 Antibody (aa64-113) - LS-C199831 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of DP-2 antibody in extracts from COS7 cells.

Anti-TFDP2 / DP2 Antibody (clone TFD5I455) - LS-C342309 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone TFD5I455
Western blot analysis of immunized recombinant protein, using anti-TFDP2 monoclonal antibody.

Anti-TFDP2 / DP2 Antibody (C-Terminus) - LS-C201213 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Thyroid Tumor. TFDP2 antibody dilution 1.0 ug/ml.

Anti-TFDP2 / DP2 Antibody (clone 2E6) - LS-C198333 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E6
TFDP2 monoclonal antibody (M01), clone 2E6. Western Blot analysis of TFDP2 expression in human colon.

DP2 Antibody - NBP2-16216 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: DP2 Antibody [NBP2-16216] - Sample (50 ug of whole cell lysate) A: Mouse Muscle, 10% SDS PAGE gel, diluted at 1:1000.

DP2 Antibody - NBP1-51202 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: DP2 Antibody [NBP1-51202] - Analysis of DP2 (D113) pAb in extracts from COS7 cells

DP2 Antibody (2E6.) - H00007029-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E6.

DP2 Antibody - H00007029-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: DP2 Antibody [H00007029-D01P] - Analysis of TFDP2 expression in transfected 293T cell line by TFDP2 polyclonal antibody.Lane 1: TFDP2 transfected lysate(43.00 KDa).Lane 2: Non-transfected lysate.
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