TFDP2

Gene Symbol TFDP2
Entrez Gene 7029
Alt Symbol DP2
Species Human
Gene Type protein-coding
Description transcription factor Dp-2 (E2F dimerization partner 2)
Other Description transcription factor Dp-2
Swissprots Q14188 Q14187 Q13331 D3DNG1 Q9UG28 B7Z8L5 E9PFC3 F8WAI2 B7Z8C8 Q6R754 Q8WU88
Accessions AAR89905 EAW78977 EAW78978 EAW78979 EAW78980 EAW78981 Q14188 AB528993 BAI47157 AK096450 AK303181 BAH13914 AK303634 BAH14001 AK314786 AL080206 CAB45775 AW673504 BC007976 BC013993 BC021113 AAH21113 BC040991 BX647881 CU676832 CU676833 DA321332 DC319314 EU446663 ABZ92192 HG496116 L40386 AAA69016 U18422 AAB60378 U35117 AAC50642 XM_005247731 XP_005247788 XM_011513101 XP_011511403 XM_011513102 XP_011511404 XM_011513103 XP_011511405 XM_011513104 XP_011511406 XM_011513105 XP_011511407 XM_011513106 XP_011511408 XM_011513107 XP_011511409 XM_011513108 XP_011511410 XM_011513109 XP_011511411 XM_011513110 XP_011511412 XM_011513111 XP_011511413 NM_001178138 NP_001171609 NM_001178139 NP_001171610 NM_001178140 NP_001171611 NM_001178141 NP_001171612 NM_001178142 NP_001171613 NM_006286 NP_006277
Function Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The TFDP2:E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812). {ECO:0000305|PubMed:20176812}.
Subcellular Location Nucleus.
Tissue Specificity High levels in heart and skeletal muscle. Also found in placenta, kidney, brain, lung and liver. The presence as well as the abundance of the different transcripts appear to vary significantly in different tissues and cell lines.
Top Pathways Cell cycle

DP-2 CRISPR/Cas9 KO Plasmid (h) - sc-418285 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DP-2 HDR Plasmid (h) - sc-418285-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DP-2 Double Nickase Plasmid (h) - sc-418285-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DP-2 Double Nickase Plasmid (h2) - sc-418285-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DP-2 CRISPR Activation Plasmid (h) - sc-418285-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DP-2 CRISPR Activation Plasmid (h2) - sc-418285-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DP-2 Lentiviral Activation Particles (h) - sc-418285-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DP-2 Lentiviral Activation Particles (h2) - sc-418285-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DP-2 siRNA (h) - sc-37815 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DP-2 shRNA Plasmid (h) - sc-37815-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DP-2 shRNA (h) Lentiviral Particles - sc-37815-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DP2 RNAi - H00007029-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU072301 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21255 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21255 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TFDP2 siRNA (Human) - CRH4803 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TFDP2 - MBS8216477 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TFDP2 (NM_006286.4) - SHH426176 from Creative biogene

Category siRNA
Species Reactivities Human

TFDP2 shRNA Plasmid (Human) - CHH4803 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TFDP2 miRNA 3'UTR clone - MiUTR3H-04716 from Creative biogene

Species Reactivities Human
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