TFDP2

Gene Symbol	TFDP2
Entrez Gene	7029
Alt Symbol	DP2
Species	Human
Gene Type	protein-coding
Description	transcription factor Dp-2 (E2F dimerization partner 2)
Other Description	transcription factor Dp-2
Swissprots	Q14188 Q14187 Q13331 D3DNG1 Q9UG28 B7Z8L5 E9PFC3 F8WAI2 B7Z8C8 Q6R754 Q8WU88
Accessions	AAR89905 EAW78977 EAW78978 EAW78979 EAW78980 EAW78981 Q14188 AB528993 BAI47157 AK096450 AK303181 BAH13914 AK303634 BAH14001 AK314786 AL080206 CAB45775 AW673504 BC007976 BC013993 BC021113 AAH21113 BC040991 BX647881 CU676832 CU676833 DA321332 DC319314 EU446663 ABZ92192 HG496116 L40386 AAA69016 U18422 AAB60378 U35117 AAC50642 XM_005247731 XP_005247788 XM_011513101 XP_011511403 XM_011513102 XP_011511404 XM_011513103 XP_011511405 XM_011513104 XP_011511406 XM_011513105 XP_011511407 XM_011513106 XP_011511408 XM_011513107 XP_011511409 XM_011513108 XP_011511410 XM_011513109 XP_011511411 XM_011513110 XP_011511412 XM_011513111 XP_011511413 NM_001178138 NP_001171609 NM_001178139 NP_001171610 NM_001178140 NP_001171611 NM_001178141 NP_001171612 NM_001178142 NP_001171613 NM_006286 NP_006277
Function	Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The TFDP2:E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812). {ECO:0000305|PubMed:20176812}.
Subcellular Location	Nucleus.
Tissue Specificity	High levels in heart and skeletal muscle. Also found in placenta, kidney, brain, lung and liver. The presence as well as the abundance of the different transcripts appear to vary significantly in different tissues and cell lines.
Top Pathways	Cell cycle

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human DP2 full length protein - ab159685 from Abcam Category Protein Source Wheat germ Species Human

Human DP2 protein fragment - ab159686 from Abcam Category Protein Source Wheat germ Species Human

TFDP2 / DP2 Antibody Blocking Peptide - LS-E13477 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human DP2 Protein - H00007029-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human DP2 Protein - H00007029-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

DP2 Blocking Peptide - abx063342 from Abbexa Category Peptide Species Human, Monkey

TFDP2 - H00007029-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

TFDP2 - H00007029-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TFDP2 - H00007029-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TFDP2 fusion protein - Ag2054 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human TFDP2, GST-tagged - TFDP2-3199H from Creative Biomart Category Protein Source E.coli Species Human

DP2 Blocking Peptide - CBP2148 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Monkey

Recombinant Adenomatosis Polyposis Coli Protein (APC) - RPC314Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Transcription factor Dp-2(TFDP2) - CSB-YP623906HU CSB-EP623906HU CSB-BP623906HU CSB-MP623906HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

DP-2 (FL) - sc-4258 WB from Santa Cruz Biotechnology Category Protein Prices $88.00 Sizes 10 µg/0.1 ml Species Human

TFDP2 (full length, N-term HIS tag) - TP760154 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

TFDP2-Blocking-Peptide-Center - BP21655c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TFDP2 Peptide, Human - M34GP15843H from Creative Peptides Category Peptide Source Synthetic. Species Human

TFDP2 peptide - orb218011 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg

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