CDX2

Gene Symbol CDX2
Entrez Gene 1045
Alt Symbol CDX-3, CDX2/AS, CDX3
Species Human
Gene Type protein-coding
Description caudal type homeobox 2
Other Description caudal type homeo box transcription factor 2|caudal type homeobox transcription factor 2|caudal-type homeobox protein 2|homeobox protein CDX-2
Swissprots Q5VTU7 Q99626 Q969L8 O00503 Q9UD92
Accessions AAD05200 CAB94779 EAX08422 Q99626 BC014461 AAH14461 BI085425 DQ893626 ABM84552 EU176674 ABW03475 KJ081251 AIJ19452 U51096 AAB40603 Y13709 CAA74038 XM_011534875 XP_011533177 XM_011534876 XP_011533178 XM_011534877 XP_011533179 XM_011534878 XP_011533180 XM_011534879 XP_011533181 XM_011534880 XP_011533182 NM_001265 NP_001256
Function Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.
Subcellular Location Nucleus.

CDX2 (D11D10) Rabbit mAb - 12306 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D11D10
Western blot analysis of extracts from various cell lines using CDX2 (D11D10) Rabbit mAb. HeLa extracts show negative or extremely low expression as expected.

CDX2 Antibody - 3977 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from DLD-1 and MCF7 (CDX2-null) cells using CDX2 Antibody.

Cdx2 (B-3) - sc-166830 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cdx2 (B-3): sc-166830. Western blot analysis of Cdx2 expression in COLO 320DM whole cell lysate.

Cdx2 (E-1) - sc-393572 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cdx2 (E-1): sc-393572. Western blot analysis of Cdx2 expression in COLO 320DM (A) and Caco-2 (B) whole cell lysates.

Cdx2 (C-20) - sc-19478 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Cdx2 (C-20): sc-19478. Western blot analysis of Cdx2 expression in COLO 320DM whole cell lysate.

Cdx2 (H-43) - sc-134468 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Cdx2 (H-43): sc-134468. Western blot analysis of Cdx2 expression in COLO 320DM whole cell lysate.

Cdx2 (K-21) - sc-130716 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
Cdx2 (K-21): sc-130716. Western blot analysis of Cdx2 expression in human placenta tissue extract.

Cdx2 (AMT28) - sc-56818 from Santa Cruz Biotechnology

Prices $279.00
Sizes 250 µl supernatant
Host Mouse
Clonality Monoclonal
Cdx2 (AMT28): sc-56818. Western blot analysis of Cdx2 expression in non-transfected: sc-117752 (A) and human Cdx2 transfected: sc-172943 (B) 293T whole cell lysates.

Anti-CDX2 antibody - ab41871 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CDX2 antibody (ab41871) at 1/25 dilution + lysate prepared from placenta

Anti-CDX2 antibody - ab136142 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CDX2 antibody (ab136142) at 1/500 dilution + HeLa cell lysate at 30 µg

Anti-CDX2 antibody [1C7] - ab115595 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 1C7
ab115595, at 10µg/ml, staining CDX2 in Formalin-fixed, Paraffin-embedded Human Small intestine tissue by Immunohistochemistry.

Anti-CDX2 antibody [3G9B9] - ab181488 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G9B9
Flow cytometric analysis of Hela cells labeling CDX2 with ab181488 at 1/200 dilution (green) compared to a negative control (red).

Anti-CDX2 antibody [AMT28] - ab15258 from Abcam

Prices $382.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone AMT28
Ab15258 staining human normal colon. Staining is localised to the nucleus.Left panel: with primary antibody at a dilution of 1:1000. Right panel: isotype control.Sections were stained using an automated system DAKO Autostainer Plus , at room temperature. Sections were rehydrated and antigen retrieved with the Dako 3-in-1 AR buffer EDTA pH 9.0 in a DAKO PT Link. Slides were peroxidase blocked in 3% H2O2 in methanol for 10 minutes. They were then blocked with Dako Protein block for 10 minutes (containing casein 0.25% in PBS), then incubated with primary antibody for 20 minutes, and detected with Dako Envision Flex amplification kit for 30 minutes. Colorimetric detection was completed with diaminobenzidine for 5 minutes. Slides were counterstained with Haematoxylin and coverslipped under DePeX. Please note that for manual staining we recommend to optimize the primary antibody concentration and incubation time (overnight incubation), and amplification may be required.

Anti-CDX2 antibody [EPR2764Y] - ab76541 from Abcam

Prices $403.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2764Y
Lane 1 : Anti-CDX2 antibody [EPR2764Y] (ab76541) at 1/1000 dilutionLanes 2 - 3 : Anti-CDX2 antibody [EPR2764Y] (ab76541) at 1/5000 dilutionLane 1 : HT29 lysateLane 2 : Colon cancer lysateLane 3 : Human small intestine lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-CDX2 antibody [EPR2764Y] (Alexa Fluor® 488) - ab195007 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2764Y
Overlay histogram showing SW480 cells stained with ab195007 (red line). The cells were fixed with 4% formaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab195007, 1/50 dilution) for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) Alexa Fluor® 488 used at the same concentration and conditions as the primary antibody. Unlabelled sample (blue line) was also used as a control.Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.This antibody gave a positive signal in SW480 fixed with 80% methanol (5 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-CDX2 antibody [EPR2764Y] (Alexa Fluor® 647) - ab195008 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2764Y
Overlay histogram showing SW480 cells stained with ab195008 (red line). The cells were fixed with 4% formaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab195008, 1/50 dilution) for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) Alexa Fluor® 647 used at the same concentration and conditions as the primary antibody. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a solid-state 25mW red diode laser (635 nm) and 675/30 bandpass filter.

Anti-CDX2 antibody [SP54] - ab101532 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone SP54
Flow cytometric analysis of rabbit anti-CDX2 (SP54) antibody ab101532(1/100) in HT29 cells (green) compared to negative control of rabbit IgG (blue).

Anti-CDX2 Antibody (aa16-30) - LS-C2982 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CDX2 Antibody (aa234-248) - LS-C6023 from LifeSpan Bioscience

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-CDX2 Antibody (aa250-300) - LS-C79032 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CDX2 Antibody (N-Terminus) - LS-C79035 from LifeSpan Bioscience

Prices $530.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal

Anti-CDX2 Antibody (Internal) - LS-C79031 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-CDX2 Antibody (N-Terminus, clone AMT28) - LS-C95609 from LifeSpan Bioscience

Prices $320.00, $435.00
Sizes 500 µl, 1 ml
Host Mouse
Clonality Monoclonal
Clone AMT28

Anti-CDX2 Antibody - LS-C149909 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-CDX2 Antibody (Internal) - LS-C34664 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
CDX2 antibody (1 ug/ml) staining of Human Kidney lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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