CYP2C8

Gene Symbol	CYP2C8
Entrez Gene	1558
Alt Symbol	CPC8, CYPIIC8, MP-12/MP-20
Species	Human
Gene Type	protein-coding
Description	cytochrome P450, family 2, subfamily C, polypeptide 8
Other Description	P450 form 1|cytochrome P450 2C8|cytochrome P450 IIC2|cytochrome P450 MP-12|cytochrome P450 MP-20|cytochrome P450 form 1|cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8|flavoprotein-linked monooxygenase|microsomal monooxygenase|s-mephenytoin 4-hydroxylase|xenobiotic monooxygenase
Swissprots	P10632 B0AZN2 Q9UCZ9 Q8WWB1 A8K9N8 Q5VX93 B7Z1F6
Accessions	AAR89907 CAA38578 EAW50016 EAW50017 EAW50018 P10632 AK292753 BAF85442 AK293327 BAH11491 AK293328 BAH11492 AK298401 BAH12777 AK303813 BAH14057 AK315823 BAF98714 BC020596 AAH20596 CD014119 DQ891400 ABM82326 DQ894579 ABM85505 M17397 AAA35739 M17398 AAA35740 M21941 AAA52160 M21942 AAA52161 X51535 CAA35915 Y00498 CAA68550 XR_945610 NM_000770 NP_000761 NM_001198853 NP_001185782 NM_001198854 NP_001185783 NM_001198855 NP_001185784 NM_030878
Function	Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. In the epoxidation of arachidonic acid it generates only 14,15- and 11,12-cis-epoxyeicosatrienoic acids. It is the principal enzyme responsible for the metabolism the anti- cancer drug paclitaxel (taxol). {ECO:0000269|PubMed:7574697}.
Subcellular Location	Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Top Pathways	Chemical carcinogenesis, Arachidonic acid metabolism, Linoleic acid metabolism, Retinol metabolism, Drug metabolism - cytochrome P450

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CYP2C8 full length protein - ab158250 from Abcam Category Protein Source Wheat germ Species Human

CYP2C8 Antibody Blocking Peptide - LS-E27748 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CYP2C8 Antibody Blocking Peptide - LS-E9410 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Cytochrome P450 2C8 Protein - H00001558-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

CYP2C8-Antibody-N-term-Blocking-Peptide - BP7995a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CYP2C8 Peptide - AC21-2559-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CYP2C8 - H00001558-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

CYP2C8 Peptide - 42-881P from ProSci Category Peptide Species Human

CYP2C8 fusion protein - Ag9898 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, T-HIS Species Human

Recombinant Human CYP2C8, His-tagged - CYP2C8-11773H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human CYP2C8, GST-tagged - CYP2C8-120H from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Human CYP2C8 - CYP2C8-384H from Creative Biomart Category Protein Source baculovirus-insect cells

Recombinant Human Cytochrome P450 2C8(CYP2C8) - CSB-YP006418HU CSB-EP006418HU CSB-BP006418HU CSB-MP006418HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CYP2C8 - TP304605 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

cytochrome P450 2C8, Peptide - MBS427568 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

Cytochrome P450 2C8 Recombinant Protein Antigen - NBP1-88055PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Cytochrome P450 2C8 Recombinant Protein Antigen - NBP1-88054PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Cytochrome P450 2C8 Blocking Peptide - abx162102 from Abbexa Category Peptide Species Human, Mouse

CYP2C8 Peptide, Human - M34GP03958H from Creative Peptides Category Peptide Source Synthetic. Species Human

Cytochrome P450 2C8 Blocking Peptide - CBP4891 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse

Cytochrome P450 2C8 (CYP2C8), Recombinant Protein - MBS949831 from MyBioSource Category Protein Prices $1,275.00, $1,275.00, $1,495.00, $1,495.00, $2,090.00, $2,090.00, $2,555.00, $2,555.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

CYP2C8 Immunizing peptide - orb59999 from Biorbyt Category Peptide

Cytochrome P450 2C8 peptide - orb316035 from Biorbyt Category Peptide

Search more