| Gene Symbol |
ADSS
|
| Entrez Gene |
159
|
| Alt Symbol |
ADEH, ADSS 2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
adenylosuccinate synthase
|
| Other Description |
AMPSase 2|IMP--aspartate ligase 2|L-type adenylosuccinate synthetase|adSS 2|adenylosuccinate synthetase (Ade(-)H-complementing)|adenylosuccinate synthetase isozyme 2|adenylosuccinate synthetase, acidic isozyme|adenylosuccinate synthetase, liver isozyme
|
| Swissprots |
P30520 B1AQM5 Q96EG7
|
| Accessions |
CAA47123 EAW77102 EAW77103 P30520 AK025514 AK303886 BAG64822 AK308749 BC012356 AAH12356 BE538442 BG700800 BI559850 EU831433 ACE87120 EU831525 ACE86444 XM_011544108 XP_011542410 XM_011544109 XP_011542411 NM_001126 NP_001117
|
| Function |
Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
|
| Subcellular Location |
Cytoplasm. Note=Partially associated with particulate fractions.
|
| Top Pathways |
Purine metabolism, Alanine, aspartate and glutamate metabolism
|
![Western Blot: Adenylosuccinate Synthase Overexpression Lysate (Adult Normal) [NBL1-07364] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Adenylosuccinate Synthase.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4996_Adenylosuccinate%2520Synthase%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07364-img0002.jpg)