Gene Symbol | ADSS |
---|---|
Entrez Gene | 159 |
Alt Symbol | ADEH, ADSS 2 |
Species | Human |
Gene Type | protein-coding |
Description | adenylosuccinate synthase |
Other Description | AMPSase 2|IMP--aspartate ligase 2|L-type adenylosuccinate synthetase|adSS 2|adenylosuccinate synthetase (Ade(-)H-complementing)|adenylosuccinate synthetase isozyme 2|adenylosuccinate synthetase, acidic isozyme|adenylosuccinate synthetase, liver isozyme |
Swissprots | P30520 B1AQM5 Q96EG7 |
Accessions | CAA47123 EAW77102 EAW77103 P30520 AK025514 AK303886 BAG64822 AK308749 BC012356 AAH12356 BE538442 BG700800 BI559850 EU831433 ACE87120 EU831525 ACE86444 XM_011544108 XP_011542410 XM_011544109 XP_011542411 NM_001126 NP_001117 |
Function | Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. |
Subcellular Location | Cytoplasm. Note=Partially associated with particulate fractions. |
Top Pathways | Purine metabolism, Alanine, aspartate and glutamate metabolism |